Apert syndrome in newborns.


Apert syndrome is a type of acrocephalosyndacty, a congenital condition which is characterized by head, face, hands, and feet malformations. It is classified as a branchial arch syndrome which affects the first branchial (or pharyngeal) arch, the maxilla precursor, and mandible. Disturbances in the formation of the branchial arches produce permanent and widespread effects in fetal development. In embryology, the hands and feet have selective cells which die in a process called selective cell death, or apoptosis, which causes digit separation. Selective cell death does not occur in the case of acrocephalosyndacty, and skin, and occasionally bone, fuses between the fingers and toes. Unlike Crouzon syndrome and Pfeiffer syndrome, the cranial bones are also affected. Craniosynostosis occurs when the skull and facial bones of the fetus merge in utero too early, interfering with normal bone development. Fusion of various sutures on the skull leads to different development patterns. Share your comments on topic Email us: clingenom@peerreviewedjournal.org Submit your submission through direct online link: https://www.scitechnol.com/submission/ For more information visit our website: https://www.scitechnol.com/ We accept more than one paper for one author you can also go for membership.