Sensory transmission in the gastrointestinal tract

Image The gastrointestinal (GI) tract must balance ostensibly opposite functions. On the one hand, it must undertake the process of digestion and absorption of nutrients. At the same time, the GI tract must protect itself from potential harmful antigenic and pathogenic material. Central to these processes is the ability to sense the mechanical and chemical environment in the gut wall and lumen in order to orchestrate the appropriate response that facilitates nutrient assimilation or the rapid expulsion through diarrhoea and/or vomiting. In this respec... Read More

CT of the Gastrointestinal Tract: Principles and Interpretation

Image The experience accumulated in daily abdominal CT scanning and CT evaluation of gastrointestinal lesions has generated helpful technical guidelines and some reliable principles of interpretatlon. These general principles are briefly discussed in this review, and the importance of performing a CT examination that is adequate for the detection and evaluation of gastrointestinal lesions is stressed. CT features useful in difterentiating benign from malignant lesions, limitations and pftfalls in CT interpretstion, overlap in the CT appearance, and classical CT features... Read More

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

Image IMPORTANCE Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and mortality worldwide since December 2019. However, information on cardiac injury in patients affected by COVID-19 is limited. OBJECTIVE To explore the association between cardiac injury and mortality in patients with COVID-19. DESIGN, SETTING, AND PARTICIPANTS This cohort study was conducted from January 20, 2020, to February 10, 2020, in a single center at Renmin Hospital of Wuhan University, Wuhan, China; the final date of follow-up was February 15, 202... Read More

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

Image Purpose: COVID-19 (coronavirus disease 2019) is a public health emergency of international concern. As of this time, there is no known effective pharmaceutical treatment, although it is much needed for patient contracting the severe form of the disease. The aim of this systematic review was to summarize the evidence regarding chlo￾roquine for the treatment of COVID-19. Methods: PubMed, EMBASE, and three trial Registries were searched for studies on the use of chloroquine in pa￾tients with COVID-19. Results: We included six articles (one narrative letter, one in-vitro ... Read More

A Therapy to Live By: Public Health, the Self and Nationalism in the Practice of a North Indian Yoga Society

Image In this article I focus on the relationship between concepts of self and health in modern North India. Drawing on field research in a popular yoga society, I argue that yoga therapy, as practiced by the Bharatiya Yog Sansthan of Delhi, provides a reconceptualization of what can be meant by public health. Using studies that challenge both the essentialist and epistemologi￾cal facticity of the self, I show how the discourse and practice of yoga is implicated in, and derived from, a complex search for self definition in terms of health; health which is... Read More

Yoga for bronchial asthma: a controlled study

Image Fifty three patients with asthma underwent training for two weeks in an integrated set of yoga exercises, including breathing exercises, suryanamaskar, yogasana (physical postures), pranayama (breath slowing techniques), dhyana (meditation), and a devotional session, and were told to practise these exercises for 65 minutes daily. They were then compared with a  controlgroup of 53 patients with asthma matched for age,sex, and type and severity of asthma, who continued to take their usual drugs. There was a significantly greater improvement in the group who practised yoga in th... Read More

Use of Mindfulness, Self-Compassion, and Yoga Practices With Low-Income and/or Uninsured Patients With Depression and/or Anxiety

Image This pilot study was conducted to determine the effectiveness of mindfulness practices, including self-compassion and yoga, on depression and/or anxiety in uninsured and/or low-income patients. Design: The design was repeated measures with one group. Method: Patients received 8 weeks of mindfulness training including self-compassion and yoga. Depression and anxiety symptoms, self-compassion, and psychological well-being were measured four times. Findings: Interventions were effective in helping uninsured and low-income patients reduce depression and/or anxiety symptoms. Conclusion: This stu... Read More

Shockwave therapy.

Image Shockwave therapy for painful disorders is an inexpensive, non-surgical treatment. Learn more about symptoms, medical results, scientific research and experience. Shockwave therapy is a common procedure used to treat shoulder trauma, chronic Achilles tendonitis, plantar fasciitis, tendinopathy of the elbow and myofascial syndrome (muscle pain) chronic levels. Accepting paper regarding field of physiotherapy you can submit your submission here: https://www.scitechnol.com/submission/ You can also Email us: physicaltherapy@scitecjournals.com For more information check the website https://www.s... Read More

GENE GUN AND DESIGN

Image A gene gun or biolistic particle delivery system is a device used to deliver exogenous DNA (transgenes), RNA, or protein to cells. By coating particles of a heavy metal with a gene of interest and firing these micro-projectiles into cells using mechanical force, an integration of desired genetic information can be induced into cells. The technique involved with such micro-projectile delivery of DNA is often referred to as biolistics. This device is able to transform almost any type of cell and is not limited t... Read More

Aquatic physiotherapy.

Image Aquatic therapy refers to water-borne therapies and activities for relaxation, wellness, physical rehabilitation and other medical gain. A certified aquatic therapist usually gives a person who is undergoing care in a heated therapy pool constant attendance. The methods used in aquatic therapy include Aqua Running, Bad Ragaz Ring Method, Burdenko Method and other types of aquatic bodywork. Which include neurological conditions, spine pain, musculoskeletal pain, postoperative orthopedic rehabilitation, developmental disabilities, and pressure ulcers. It refers to water-based therapies or the... Read More

Flow cytometry

Image Flow cytometry (FCM) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles.In this process, a sample containing cells or particles is suspended in a fluid and injected into the flow cytometer instrument. The sample is focused to ideally flow one cell at a time through a laser beam, where the light scattered is characteristic to the cells and their components. Cells are often labeled with fluorescent markers so light is absorbed and then emitted in a band of wavelengths. Tens of thousands of cells can be quic... Read More

SDS-PAGE

Image SDS-PAGE is an electrophoresis method that allows protein separation by mass. The medium (also referred to as ′matrix′) is a polyacrylamide-based discontinuous gel.SDS-PAGE (sodium dodecyl sulfate–polyacrylamide gel electrophoresis), the use of sodium dodecyl sulfate and polyacrylamide gel largely eliminates the influence of the structure and charge, and proteins are separated solely based on polypeptide chain length. It uses sodium dodecyl sulfate (SDS) molecules to help identify and isolate protein molecules.SDS-PAGE is a discontin... Read More

Current physiotherapy.

Image Interferential current therapy is an effective therapy option used by many physiotherapy clinics to relieve pain and accelerate the self-healing process, getting your body back to a healthy, pain Free State. The high frequency signals of an IFC penetrate through the skin into deeper lying muscle tissues. Electrodes are placed on your skin around the injured body part. The Interferential Current device then transmits electrical impulses in minute quantities through your skin. Underlying tissue and nerves are stimulated which begins the healing properties. These impulses are not painful in th... Read More

Temporomandibular Joint.

Image Neck Pain may be linked to other neighboring disorders such as the Temporomandibular Joint (TMJ). This study aimed to investigate whether there is benefit in incorporating TMJ therapies to routine physiotherapy compared to a control group in patients with non-specific chronic neck pain. Left untreated, the TMJ problems can get more serious and more difficult to treat at the same time. Chronic, severe headaches may cause TMJ disorder. Another common issue with untreated TMJ disorder is deterioration of the dentistry. The irregular surface of a bite is one cause of TMJ dysfunction. Accepting ... Read More

Integrating Yoga Therapy in the Management of Urinary Incontinence: A Case Report

Image The Journal focuses on integrative medicine, urinary incontinence, yoga.A 63-year-old overweight female prediagnosed of stress urinary incontinence presented with exacerbated events of urine leakage. She was advised a residential lifestyle and behavioral program, primarily consisting of a monitored yoga therapy module, apart from her ongoing anticholinergic medicine, for 21 days. Assessments were based on a frequency volume chart, a bladder diary for the entire duration of treatment, and the International Consultation on Incontinence Modular Questionnaire-Urinary Incontinence Short For... Read More

A National Survey of Yoga Instructors and their Delivery of Yoga Therapy

Image Yoga therapy may improve a variety of symptoms and health conditions, but little is known about how yoga therapy is being delivered in the real world. The purpose of this study was to describe the delivery of yoga therapy by yoga instructors across the U.S. In this cross-sectional survey, certified instructors were recruited from the Iyengar Yoga National Association, United States (IYNAUS) (n = 966) via an email that contained a link to an anonymous online survey that collected information on demographics, their delivery of yoga therapy, and the health conditions and symptoms seen... Read More

The OTSC Proctology clip system for anal fistula closure: First prospective clinical data

Image Anorectal fistulas represen ta troublesome condition for both patient and surgeon.TheOTSC Proctologyclip system is a new device for transanal anorectal fistula closure. The OTSC Proctology system was evaluated in a prospective clinical study undertaken in two surgical proctological centers. Ten patients (three women, seven men; median age 55 years, range 25-73 years) with nine transsphincteric and one suprasphincteric fistulas were enrolled into thestudy. Themedianoperationtimewas30minutes(range20-45minutes).Therewerenointraoperativetechnical or surgical complications. Postoperatively, n... Read More

Prospective pilot study of anorectal fistula closure with the OTSC Proctology

Image The OTSC Proctology is a surgical device for anorectal fistula closure. It consists of a super-elastic nitinol clip, which is placed (with the aid of a transanal applicator) on the internal fistula opening to achieve healing of the fistula track. A prospective, two-centre clinical pilot study was undertaken to assess the efficacy and safety of the OTSC Proctology in patients with a complex high anorectal fistula. Method In patients with a complex anorectal fistula the primary track was debrided using a special brush and the clip was applied to the internal fistula opening. Aft... Read More

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

Image The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China ... Read More

Discovering drugs to treat coronavirus disease 2019 (COVID-19)

Image The SARS-CoV-2 virus emerged in December 2019 and then spread rapidly worldwide, particularly to China, Japan, and South Korea. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of coronavirus disease 2019 (COVID-19) in China; some promising results have been achieved thus far. This article summarizes agents with potential efficacy against SARS-CoV-2. The virus SARS-CoV-2 (formerly designated 2019nCo... Read More

Chest therapy for better respiration.

Image Chest physical therapy is the term used for a community of therapies aimed at enhancing respiratory performance, encouraging lung expansion, strengthening respiratory muscles and reducing respiratory secretions. Healthy respiratory safety can't be done without effective clearance of airway secretions. This is usually achieved in a healthy person by means of two mechanisms: mucociliar clearance system (MCS) and cough capacity. Children have numerous illnesses and disorders due to poor lung health and an impaired capacity to clear secretions. The purpose of chest physical therapy, also kn... Read More

Electroblotting and its procedure

Image Electroblotting is a method in molecularbiology /biochemistry/immunogenetics to transfer proteins or nucleic acids onto a membrane by using PVDF or nitrocellulose, after gel electrophoresis.The protein or nucleic acid can then be further analyzed using probes such as specific antibodies, ligands like lectins, or stains. This method can be used with all polyacrylamide and agarose gels. An alternative technique for transferring proteins from a gel is capillary blotting. DEVELOPMENT ... Read More

Hydroxychloroquine in the treatment of COVID-19

Image COVID-19 is a new illness that can affect your lungs and airways. It's caused by a virus called coronavirus. Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2. The disease was first identified in December 2019 in Wuhan, the capital of China's Hubei province, and has since spread globally, resulting in the ongoing 2019–20 coronavirus pandemic. The first confirmed case of what was then an unknown coronavirus was traced back to November 2019 in Hubei province.Common ... Read More

Multiple sclerosis: Its causes and genetics

Image Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. While the cause is unclear, the underlying mechanism is thought to be either destruction by the immune system or failure of the myelin-producing cells. CAUSES: The cause of MS is unknown; however, it is believed to occur as a result of some combination of genetic and environmental factors such as infectious agents. Theories try to combine the data into likely... Read More

Range of motion for better result.

Image The motion range (or ROM) is the linear or angular distance that a moving body will usually move while properly connected to another body. It is also called travel range (or ROT), particularly when thinking about mechanical devices and in fields of mechanical engineering. As used in the biomedical field and by weightlifters, motion range refers to the distance and direction that a joint will travel between the flexed position and the extended position. The act of attempting to increase this distance through therapeutic exercises (range of motion therapy — stretching for physiological ... Read More

Integrating Yoga Into Cancer Care

Image Although yoga has been practiced in Eastern culture for thousands of years as part of life philosophy, classes in the United States only recently have been offered to people with cancer. The word yoga is derived from the Sanskrit root yuj, meaning to bind, join, and yoke. This reflection of the union of the body, mind, and spirit is what differentiates yoga from general exercise programs. Yoga classes in the United States generally consist of asanas (postures), which are designed to exercise every muscle, nerve, and gland in the body. The postures are combined with pranayama, or rhythmic co... Read More

Yoga Ameliorates Performance Anxiety and Mood Disturbance in Young Professional Musicians

Image Yoga and meditation can alleviate stress, anxiety, mood disturbance, and musculoskeletal problems, and can enhance cognitive and physical performance. Professional musicians experience high levels of stress, performance anxiety, and debilitating performance-related musculoskeletal disorders (PRMDs). The goal of this controlled study was to evaluate the benefits of yoga and meditation for musicians. Young adult professional musicians who volunteered to participate in a 2-month program of yoga and meditation were randomized to a yoga lifestyle intervention group (n = 15) or to a group practi... Read More

The risk of colorectal cancer in ulcerative colitis: a meta-analysis

Image Controversy surroundstheriskofcolorectalcancer(CRC) in ulcerative colitis (UC). Many studies have investigated this risk and reported widely varying rates. A literature search using Medline with the explosion of references identified 194 studies. Of these, 116 met our inclusion criteria from which the number of patients and cancers detected could be extracted. Overall pooled estimates,with95%confidenceintervals(CI), of cancer prevalence and incidence were obtained using a random eVects model on either the log odds or log incidence scale, as appropriate. The overall prevalence of CRC in an... Read More

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

Image  Reduced methylation of DNA may contribute to loss of the normal controls on proto-oncogene expression. In humans, hypomethylation of DNA has been observed in colorectal cancers and in their adenomatous polyp precursors. Accumulation of DNA methylation abnormalities, observed during progression of human colorectal neoplasia, may be influenced by certain dietary factors. The apparent protective effect of fresh fruits and vegetables, the major folate sources, on colorectal cancer incidence suggests that a methyldeficient diet contributes to occurrence of this malignancy. Low dietary fola... Read More

Evaluating Hallucinogenic or Psychedelic Drug Intoxication in an Emergency Setting

Image Under certain conditions or in an overdose setting, several classes of drugs can induce illusions, hallucinations, or delusions. However, one of the hallmark features of hallucinogens or psychedelic agents is their ability to induce states of altered or distorted perception, thought, and mood. Many hallucinogens produce classic sympathomimetic effects; that is, hyperactivity, mydriasis (dilated pupils), hypertension, tachycardia, and hyperthermia. However, the effects vary considerably, depending upon the hallucinogen ingested. Qualitative confirmation by the laboratory that the patient is ... Read More

Impacts of Drugs on Neurotransmission

Image Drugs of abuse alter the way people think, feel, and behave by disrupting neurotransmission, the process of communication between brain cells. Over the past few decades, studies have established that drug dependence and addiction are features of an organic brain disease caused by drugs' cumulative impacts on neurotransmission. Scientists continue to build on this essential understanding with experiments to further elucidate the physiological bases for drug abuse vulnerability as well as the full dimensions and progression of the disease. The findings provide powerful leads to new medica... Read More

Spine Chilling CORONA Virus

Image SARS Covid-19 pandemic has devastated the entire globe. As we are aware of the fact that the corona virus enters our body through the mouth, nose and ears. We are provided with only the information about the overview of the effects of the virus but not in detail. The corona affected patients who have now recovered from the condition might not be having the in detailed information of the precautionary measures to be taken to improve the health condition of their nose and throat and this may lead to further medical complications. Being the source of an Electronic print media, the ... Read More

Transplantation and Medical Surgery

Image Transplantation has been a boon for patients (like infants, children, middle aged, aged, etc.) who suffer with various types cancers to lead a health life. Every day on an average 20 people die around the globe. One deceased donor can save up to eight lives through organ donation and can save and enhance more than 100 lives through the lifesaving and healing gift of tissue donation. Organs that can be donated after death are the heart, liver, kidneys, lungs, pancreas and small intestines. Tissues include corneas, skin, veins, heart valves, tendons, ligaments and bones. A healthy person can ... Read More

Self-rated Masticatory Ability and Independent Life in Community Dwelling Elderly Populations

Image Poor chewing ability is associated with deterioration in the quality of life in older adults. Little is known about how self-rated chewing ability is related with an independent life in communitydwelling older adults. This study examined whether self-rated chewing ability was associated with independent life in communitydwelling older people. Methods: This cross-sectional study assessed 1,377 subjects over the age of 65 who lived in Kumamoto City, Japan (mean age 79.8 years). Participants divided three groups based on their selfrated chewing ability; good, fair and poor. We assessed needs f... Read More

Age Dependent Changes of Biological Properties in the Multipotent Mesenchymal Stromal Bone Marrow Cells in FVB Mice

Image In the last years researchers’ attention has been given to the immunomodulatory properties of multipotent mesenchymal stromal cells. The question of effectiveness of the stem cell therapy with MSCs from elderly donors is worth studying. Our aim was to compare the potency of bone marrow MSCs in aging. Methods: BM-MSCs were obtained using the standard methods. The following methods were applied: immunophenotyping, colony-forming unit fibroblasts assay, granulocyte/macrophage colony-forming cells assay in the semi-agar cultures, directed differentiation, colorimetric method, MTT assay. R... Read More

Prostate-specific antigen test

Image Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely.&nb... Read More

Cardiopulmonary bypass

Image Cardiopulmonary bypass (CPB) is a technique in which a machine temporarily takes over the function of the heart and lungs during surgery, maintaining the circulation of blood and the oxygen content of the patient's body. The CPB pump itself is often referred to as a heart–lung machine or "the pump". Cardiopulmonary bypass pumps are operated by perfusionists. CPB is a form of extracorporeal circulation. Extracorporeal membrane oxygenation is generally used for longer-term treatment. CPB mechanicall... Read More

The Effects of 1-Aminobenzotriazole Inhibition on the Formation of Acyl-Glucuronide and Acyl-Glutathione Metabolites in Rat Hepatocytes

Image 1-Aminobenzotriaole (ABT) is a commonly used non-selective mechanism based human and non-human cytochrome P450 (P450) inactivator. However, the direct effects of ABT mediated P450 inhibition on conjugative metabolism, specifically acyl-glucuronide and acyl-glutathione formation has not been previously investigated. In the present study, we evaluated t... Read More

Are Both Antidepressant Drug Effects and Test Scores Unspecific?

Image Disappointingly small clinical effects of antidepressant drugs have recently been reemphasized. It is also unclear to what degree the 17 questions in the Hamilton Rating Scale of Depression and other questionnaires represent true aspects of depression or rather can be said to measure unspecific symptoms. Methods: Within all clinical study reports concerning citalopram submitted to the Danish Health Authoritie... Read More

The influence of Hatha yoga as an add-on treatment in major depression on hypothalamicepituitaryeadrenal-axis activity: A randomized trial

Image The impact of Hatha yoga as add-on treatment to quetiapine fumarate extended release (QXR) or escitalopram (ESC) in depressed patients on hypothalamicepituitaryeadrenal (HPA) axis activity was assessed. 60 inpatients suffering from major depressive disorder (MDD) according to DSM-IV were randomized for a 5 week treatment with Yoga or not (control group) and with either QXR (300 mg/day) or ESC (10 mg/day). Serial dexamethasone/corticotropin releasing hormone (DEX/CRH) tests were performed to assess HPA axis function. The Hamilton Depression Rating Scale (21-HAMD) was used weekly.  A mor... Read More

Back and neck pain in office workers.

Image Sitting at a desk is a common source of back and neck discomfort, mostly because you're accommodating instead of the other way around to your workstation. For example, many people are straining to see a computer display that is too distant, too low, too high, too tiny or too dim. This makes healthy posture compromised. The average human head weighs approximately 12 pounds (5.4 kg)—the size of a bowling ball! Your head exerts approximately 23 kilograms of force on your neck when your back is bent to 45 degrees. The pressure impacts your breathing and attitude in addition to straini... Read More

Effects of Yoga on Mental and Physical Health

Image The conceptual background of yoga has its origins in ancient Indian philosophy. There are numerous modern schools or types of yoga (i.e., Iyengar, Viniyoga, Sivananda, etc.), each having its own distinct emphasis regarding the relative contentofphysicalposturesandexercises(asanas),breathing techniques (pranayama), deep relaxation, and meditation practices that cultivate awareness and ultimately more profound states of consciousness. The application of yoga as a therapeutic intervention, which began early in the twentieth century, takes advantage of the various psychophysiological benefits ... Read More

Stability Study of Fifteen Synthetic Cannabinoids of Aminoalkylindole Type in Whole Blood, Stored in Vacutainer® Evacuated Glass Tubes

Image The aim of this study was to evaluate the stability of blood concentrations of a variety of synthetic cannabinoids when spiked and stored in Vacutainer® evacuated glass tubes. Analysis for synthetic cannabinoids will be of less importance if the compounds disappear during transportation, and thus the previous must be tested for the specific tubes used during... Read More

Methadone Related Deaths: Identifying The Vulnerable Patients

Image Methadone has been used in opioid dependence treatment since the 1960s and is now prescribed also as a chronic pain treatment. Even though its effectiveness has been worldwide assessed, literature reports several cases of death associated with the administration of this drug. Risk factors are still uncertain and the frequent combination with other substances of abuse makes it even more difficult to determine the exact ro... Read More

Management of hepatitis C; Report of the Consensus Meeting at the 45th Annual Meeting of the Japan Society of Hepatology

Image The consensus meeting for the diagnosis, management and treatment for hepatitis C was held in 45th annual meeting for the Japan Society of Hepatology (JSH) in June 2009 where the recommendations and informative statements were discussed including organizers and presenters. The Several important informative statements and recommendations have been shown.This was the fourth JSH consensus meeting of hepatitis C, however, the recommendations have not been published in English previously. Thus, this is the first report of JSH consensus of hepatitis C. The rate of development of hepatocellular c... Read More

the Infectious Complications of Interventional Radiology Based Procedures in Gastroenterology and hepatology

Image Many interventional radiology (IR) procedures are used to manage gastroenterological and hepatobiliary diseases. One of the most common complications of any IR procedure is infection. Literature published in English from January 1960 to August 2010 pertaining to the infectious complications of IR in gastroenterology and hepatology patients was examined by electronic search (Medline and the National Library of Medicine, Embase and the Cochrane Library). Percutaneous transhepatic cholangiogram (PTC) and biliary drainage, trans-arterial chemoembolization (TACE), transjugular intrahepatic porto... Read More

A review of pharmacological properties, pharmacognosy and therapeutic actions of Putranjiva roxburghii Wall. (Putranjiva)

Image Putranjiva roxburghii Wall. is a well-known plant which has been ascribed an important role in Ayurvedic texts as an antipyretic, anti-inflammatory & anti-rheumatic herb useful in gynaecological and fertility ailments. The pharmacognosy of its leaves, fruits, root and stem bark indicates the presence of many glycosides, saponins, triterpenes and flavonoids. Its leaf extract has been found suitable in biological methods of gold nanoparticle production. During pharmacological analysis, its leaf extract exhibited significant anti-hyperglycemic, analgesic, antipyretic and anti-inflammatory ... Read More

STEM BARK OF MANILKARA HEXANDRA (ROXB.)DUBARD – PHARMACOGNOSY

Image Manilkara hexandra (Roxb.) Dubard commonly known as Rayan/ Khirni is an evergreen tree of Western ghats (Maharashtra) India. Itbelongs to the family Sapotaceae. The fruit of this tree is edible and is available in the markets. While the bark is used in curing fever, flatulence, stomach disorder, etc. by the aboriginals. However, the said plant part is studied for the first time. The present investigation deals with the pharmacognostical studies on the stem bark of the above plant. For Pharmacognostical evaluation macroscopy, microscopy, powder study and histochemical analysis of stem bark w... Read More

Knee effusion in different age group people.

Image Knee effusion happens when excess synovial fluid builds up in or around the knee joint. This has many common causes including arthritis, ligament damage or meniscus damage, or bursa fluid accumulation, a condition known as pre-patellar bursitis. Signs and symptoms of water on the knee are contingent on the origin of excess synovial fluid build-up in the knee joint. They may include: Pain, Swelling, Stiffness, and Bruising. Swelling causes may involve arthritis, knee ligament damage or an incident in which the body's normal response is to cover the knee with a defensive fluid. There may ... Read More

A Study on the Effect of Yogic Intervention on Anxiety

Image  Anxiety is one of the important psychological problems people facing now days. Approximately 40 million American adults ages 18 and older, or about 18.1 percent of people in this age group in the year 2005, have an anxiety disorder.  Contemporary researches done in the area of ‘Yogic intervention and their effect over various parameters of Psychological health’ provoked the researcher to attempt an individual project to judge the effect of Yoga on normal people at the level of anxiety. To observe the effect of Yoga on anxiety level of the normal people a pre - post re... Read More

Integrating Yoga with Psychotherapy: A Complementary Treatment for Anxiety and Depression

Image Yoga reduced anxiety for people with state, trait, and performance anxiety as well as for people with PTSD. The breath work practice, meditation practice, and learning about yoga practices decreased feelings of anxiety, whereas the physical postures decreased the physical symptoms of tension and anxiety. Given that yoga was found to be as effective as conventional relaxation techniques in reducing stress and anxiety, people with anxiety may wish to also consider the unconventional relaxation techniques of yoga. Yoga reduced depression for people with many forms of depression, including thos... Read More

Topography of efferent vagal innervation of the rat gastrointestinal tract

Image The gastrointestinal territories innervated by the gastric, celiac, and hepatic abdominal vagi were identified in rats with selective branch vagotomies by means of 1) anterograde tracing with the carbocyanine dye DiI injected into the dorsal motor nucleus and 2) measurement of cervical vagal stimulation-induced motility responses throughout the gut axis. Presence of DiI-labeled vagal terminals in the myenteric plexus and evoked motility responses were well correlated across the sampled gastrointestinal (GI) sites. In animals with only the two gastric branches intact, the entire stomach and ... Read More

Serum a-Fetoprotein in Patients with Neoplasms of the Gastrointestinal Tract'

Image Serum a-fetoprotein levels were measured by a sensitive double-antibody radioimmunoassay in 580 patients with a variety of malignant and nonmalignant gastrointestinal diseases to determine the incidence of levels elevated above 40 ng/ml. Over 200 normal control subjects have all had levels below 40 ng/ml. Fifteen % of 95 patients with gastric carcinoma, 3% of 191 patients with colorectal carcinoma, 24% of 45 patients with pancreatic carcinoma, 25% of 8 patients with biliary tract carcinoma, and 70% of73 patients with hepatocellular carcinoma had elevated serum a-feto protein. None of 14 pat... Read More

OccurrenceandEnvironmental BehavioroftheChiral PharmaceuticalDrugIbuprofenin SurfaceWatersandinWastewater

Image Pharmaceutical compounds can reach detectable concentrations in rivers and lakes if production and use aresufficientlylargeandthecompoundsshowsomemobility and persistence in the aquatic environment. In this study, we report on the occurrence and on the enantiomer composition of the chiral pharmaceutical drug ibuprofen (IB) in surface waters and in samples from wastewater treatment plants (WWTPs). Enantioselective gas chromatography and detection by mass spectrometry/mass spectrometry was used for analysis. IB was present in influents of WWTPs at concentrations of up to 3 µg/L with a h... Read More

Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies

Image HepaRG cells, a newly developed human hepatoma cell line, differentiate into hepatocyte-like morphology by treatment with dimethyl sulfoxide (DMSO). The expression of cytochrome P450 (P450) enzymes, transporter proteins, and transcription factors was stable in differentiated HepaRG cells over a period of 6 weeks when cultured with DMSO. Compared with human hepatocytes, expression of P450 in HepaRG cells was in general lower with the exception for a considerably higher expression of CYP3A4 and CYP7A1. The expression of P450s generally decreased when DMSO was removed from the medium, whereas ... Read More

Frozen shoulder shows up in adults.

Image Frozen shoulder is a condition which affects the joint in your shoulder. It typically involves pain and stiffness which slowly grows, gets worse and eventually goes away. It can take from a year to 3 years, anywhere. The shoulder consists of three bones, forming a ball-and-socket joint. It is a disease in the shoulder joint which is characterized by stiffness and pain. Symptoms can start slowly and improve within one to two years. Treatment includes stretching and often injecting corticosteroids and numbing medication into the joint capsule. The condition occurs more frequently in people wi... Read More

Impedance phlebography

Image Impedance phlebography, is a non-invasive medical test that measures small changes in electrical resistance of the chest, calf or other regions of the body. These measurements reflect blood volume changes, and can indirectly indicate the presence or absence of venous thrombosis. This procedure provides an alternative to venography, which is invasive and requires a great deal of skill to execute adequately and interpret accurately. For the chest, the technique was developed by NASA to measure the split second impedance changes withi... Read More

Hemofiltration

Image Hemofiltration/ haemofiltration, is a renal replacement therapy which is used in the intensive care setting. It is usually used to treat acute kidney injury (AKI), but may be of benefit in multiple organ dysfunction syndrome or sepsis. During hemofiltration, a patient's blood is passed through a set of tubing (a filtration circuit) via a machine to a semipermeable membrane (the filter) where waste products and water (collectively called ultrafiltrate) are removed by conve... Read More

Psoriatic arthritis effect in adults.

Image Psoriatic arthritis is a type of arthritis that affects certain people with psoriasis a disease that features red skin patches surmounted with silvery scales. Many people first develop psoriasis and are then diagnosed with psoriatic arthritis, but sometimes the joint problems will begin before patches of the skin appear. It is a type of arthritis that affects psoriasis in some people with the skin condition. Psoriatic arthritis is a form of arthritis with an inflammation. Symptoms include pain in the joints; weakness and swelling that may intensify and subside. Most people with the disorder... Read More

Potential False Negatives in the Molecular Diagnostics of COVID-19 Infection: Experience of an Italian Laboratory during the COVID-19 Epidemic

Image The Journal Focuses on COVID-19, and Molecular diagnostics.The current situation in the molecular diagnostics field applied to the SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona virus 2) virus detection has forced various laboratories to quickly offer a solution for the identification of the infected people in this pandemic scenario recently declared by the World Health Organization. In the epidemiological emergency, the rapid commercialization of CE-IVD kits pushed numerous hospitals to adopt these methods without complete internal validations that would allow evaluating the a... Read More

Supervised training based hand gesture recognition system

Image We have developed a hand gesture recognition system, based on the shape analysis of static gestures, for Human Computer Interaction purposes. Our appearance-based recognition uses modified Fourier descriptors for the classification of hand shapes. As always found in literature, such recognition systems consist of two phases: training and recognition. In our new practical approach, following the chosen appearance-based model, training and recognition is done in an interactive supervised way: the adaptation for untrained gestures is also solved by hand signals. Our experimental results with t... Read More

Current techniques for assessing physical exposure to workrelated musculoskeletal risks, with emphasis on posture-based methods

Image The Journal focuses on Musculoskeletal disorders, Risk factors Exposure assessment, and Posture; Interaction.Physical exposure to risks for potential work-related musculoskeletal injuries has been assessed using a variety of methods, including pen and paper based observation methods, videotaping and computer-aided analysis, direct or instrumental techniques, and various approaches to self-report assessment. These methods are critically reviewed in this paper. The applications of these techniques in ergonomic and epidemiologic studies are considered, and their advantages and shortcoming... Read More

Dysbiosis in inflammatory bowel disease

Image Abundant data have incriminated intestinal bacteria in the initiation and amplification stages of inflammatory bowel diseases (IBD).12The role of the NOD2/CARD15 Crohn’s disease (CD) susceptibility gene in bacterial peptidoglycan recognition strengthens the links between enteric bacteria and mucosal inflammation.3–5 Despite these advances, the precise role of intestinal bacteria remains elusive. Nonmutually exclusive theories have included: an unidentified persistent pathogen; an abnormally permeable mucosal barrier leading to excessive bacterial translocation; an immune system ... Read More

Enhanced Synthesis of Leukotriene B4 by Colonic Mucosa in Inflammatory Bowel Disease

Image Leukotriene B4, an arachidonic acid metabolite, is a potent chemotactic agent, and is thought to be an important mediator of inflammation. To investigate the role of this compound as a mediator of inflammation in inflammatory bowel disease, arachidonic acid was incubated with ionophore and colonic mucosa from patients with inflammatory bowel disease and from normal subjects. Mucosa from patients with inflammatory bowel disease converted 2.17% of exogenous arachidonate to leukotriene B4; mucosa from normal subjects converted 0.37%. The production of leukotriene was blocked by sulfasalazine. ... Read More

Toxicology: Past, Present, and Future

Image Toxicology is the study of poisons and poisoning and has an ancient and venerable history. Although there have been numerous notorious poisonings throughout the ages and rather astute descriptions of toxic agents, the scientific study of toxicology did not commence until the 19th century. There was rapid development of analytical methods in the late 19th century and then an acceleration of both method and scientific development in the latter half of the 20th century. Toxicology today can be subdivided into clinical toxicology, forensic toxicology, industrial or occupational toxicology, envi... Read More

The selection of marmoset monkeys ( Callithrix jacchus) in pharmaceutical toxicology

Image The Journal focuses on Marmoset, Callithrixjacchus, pathology, toxicology, ferret, and minipig. Priortocontrolledclinicaltrialsinhumanvolunteersorpatientsitisrequiredthatnovel pharmaceuticalsareevaluatedforpre-clinicalsafetyinarodentandanon-rodent(`second’) species.Inmostcasestherodentspeciesusedhasbeentheratandthesecondspecieshasbeen thedogormacaque(usuallycynomolgusorrhesus)monkey.However,thereisanincreasing trendwithintheUnitedKingdom(UK)pharmaceuticalindustrytousethecommon marmoset (Callithrixjacchus )forpre-clinicaltoxicologyprogrammes. Thispaperexaminesthepracticalityofusin... Read More

Sports injury occurs while participating in a sport to sportsman.

Image Sport accidents occur during training, or during a sport. Kids are especially at risk for these kinds of accidents, but adults may also get them. Different sports injuries cause various signs and complications. Among the most common forms of sport injuries are: Sprains, Strains, Knee injuries, swollen muscles, Achilles tendon rupture, Fractures, Dislocations, Rotator cuff injury. Looks like sport injury or feels serious make an appointment to see the doctor. Seek emergency medical attention if the damaged joint shows signs of: severe swelling and pain, visible lumps, bumps, or other deformi... Read More

Obstetrics & gynecology

Image Obstetrics and gynaecology (British English) or obstetrics and gynecology (American English) is the medical specialty that encompasses the two subspecialties of obstetrics (covering pregnancy, childbirth, and the postpartum period) and gynaecology (covering the health of the female reproductive system – vagina, uterus, ovaries, and breasts). It is commonly abbreviated as OB-GYN or OB/GYN in US English, and as obs and gynae or O&G in British English. Postgraduate training programs for both fields are usually combined, preparing the practicing obstetrician-gynecologist to be adept b... Read More

Infertility

Image Infertility is the inability of a person, animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects). In humans, infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner. There are many causes of infertility, including some that medical intervention can treat. Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infer... Read More

Polycystic ovary syndrome

Image Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens (male hormones) in females.Signs and symptoms of PCOS include irregular or no menstrual periods, heavy periods, excess body and facial hair, acne, pelvic pain, difficulty getting pregnant, and patches of thick, darker, velvety skin. Associated conditions include type 2 diabetes, obesity, obstructive sleep apnea, heart disease, mood disorders, and endometrial cancer. PCOS is due to a combination of genetic and environmental factors. Risk factors include obesity, a lack of physical exercise, and a family history o... Read More

Reproductive biology

Image Reproductive biology includes both sexual and asexual reproduction. Reproductive biology includes a wide number of fields: Reproductive systems, Endocrinology, Sexual development (Puberty), Sexual maturity, Reproduction, Fertility. Endocrinology - Human reproductive biology is primarily controlled through hormones, which send signals to the human reproductive structures to influence growth and maturation. These hormones are secreted by endocrine glands, and spread to different tissues in the human body. In humans, the pituitary gland synthesizes hormones used to control the activity of endo... Read More

Reproductive technology

Image Reproductive technology encompasses all current and anticipated uses of technology in human and animal reproduction, including assisted reproductive technology, contraception and others. It is also termed Assisted Reproductive Technology, where it entails an array of appliances and procedures that enable the realization of safe, improved and healthier reproduction. While this is not true of all men and women, for an array of married couples, the ability to have children is vital. But through the technology, infertile couples have been provided with options that would allow them to conceive ... Read More

Sex organ

Image A sex organ (or reproductive organ) is any part of an animal's body that is involved in sexual reproduction. The reproductive organs together constitute the reproductive system. The testis in the male, and the ovary in the female, are called the primary sex organs. All others are called secondary sex organs, divided between the external sex organs—the genitals or genitalia, visible at birth in both sexes—and the internal sex organs. Mosses, ferns, and some similar plants have gametangia for reproductive organs, which are part of the gametophyte.The flowers of flowering plant... Read More

Sexual dysfunction

Image Sexual dysfunction is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm. According to the DSM-5, sexual dysfunction requires a person to feel extreme distress and interpersonal strain for a minimum of six months (excluding substance or medication-induced sexual dysfunction).Sexual dysfunctions can have a profound impact on an individual's perceived quality of sexual life. The term sexual disorder may not only refer to physical sexual dysfunction, but to paraphilias as well;... Read More

Urogynecology

Image Urogynecology or urogynaecology is a surgical sub-specialty of urology and gynecology. Urogynecology is a sub-specialty of Gynecology, and in some countries is also known as Female Pelvic Medicine and Reconstructive Surgery. A urogynecologist manages clinical problems associated with dysfunction of the pelvic floor and bladder. Pelvic floor disorders affect the bladder, reproductive organs, and bowels. Common pelvic floor disorders include urinary incontinence, pelvic organ prolapse and fecal incontinence. Increasingly, Urogynecologists are also responsible for the care of women who have ex... Read More

Thrombosiss

Image Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. Thrombosis may occur in veins (venous thrombosis) or in arteries (arterial thrombosis). Venous throm... Read More

Hematologyy

Image Hematology, also spelled haematology, is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood.It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. Such diseases might include hemophilia, blood clots (thrombus), other bleeding disorders, and blood cancers such as leukemia, multiple myeloma, and lymphoma. The laboratory work that goes into the study of blood ... Read More

Leukemiaa

Image Leukemia, also spelled leukaemia, is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells.These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, feeling tired, fever, and an increased risk of infections.These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown.A combination of genetic factors and environmental (non-inherited) factors are believed ... Read More

Hemostasis

Image Hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage). It is the first stage of wound healing. This involves coagulation, blood changing from a liquid to a gel. Intact blood vessels are central to moderating blood's tendency to form clots. The endothelial cells of intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin and prevent platelet aggregation with nitric oxide and prostacyclin. When endothelial injury occurs, the endothelial cells stop secr... Read More

Hemoglobin

Image Hemoglobin (American English) or haemoglobin (British English) (/ˈhiːməˌɡloʊbɪn, ˈhɛ-, -moʊ-/), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the lungs or gills to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metaboli... Read More

Circulatory Systems

Image The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis. The circulatory system includes the lymphatic system, which circulates lymph.The passage of lymph takes much longer than that of blood.Blood is a fluid consisting of plasma, red blood cells, w... Read More

Blood

Image Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells. In vertebrates, it is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume),and contains proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. Albumin is the main protein in plasma, and it functions to regulate the colloidal o... Read More

Anemia

Image Anemia (also spelled anaemia) is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood,or a lowered ability of the blood to carry oxygen.When anemia comes on slowly, the symptoms are often vague and may include feeling tired, weakness, shortness of breath, and a poor ability to exercise.When the anemia comes on quickly, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst.Anemia must be significant before a person becomes noticeably pale. Additional symptoms may occur depending on the underlying caus... Read More

Thyroid

Image The thyroid, or thyroid gland, is an endocrine gland in the neck consisting of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the thyroid isthmus. The thyroid is located at the front of the neck, below the Adam's apple. Microscopically, the functional unit of the thyroid gland is the spherical thyroid follicle, lined with follicular cells (thyrocytes), and occasional parafollicular cells that surround a lumen containing colloid. The thyroid gland secretes three hormones: the two thyroid hormones – triiodothyronine ( T3), and th... Read More

Obesity

Image Obesity is a medical condition in which excess body fat has accumulated to an extent that it may have a negative effect on health. People are generally considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight by the square of the person's height, is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower values. Obesity increases the likelihood of various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, osteo... Read More

Metabolisms

Image Metabolism is the set of life-sustaining chemical reactions in organisms. The three main purposes of metabolism are: the conversion of food to energy to run cellular processes; the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of nitrogenous wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. (The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the tr... Read More

Hormoness

Image A hormone is any member of a class of signaling molecules, produced by glands in multicellular organisms, that are transported by the circulatory system to target distant organs to regulate physiology and behavior.Hormones have diverse chemical structures, mainly of three classes: eicosanoids, steroids amino acid/protein derivatives (amines, peptides, and proteins).The glands that secrete hormones comprise the endocrine signaling system. The term "hormone" is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signali... Read More

Glucose

Image Glucose is a simple sugar with the molecular formula C6H12O6. Glucose is the most abundant monosaccharide,a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight, where it is used to make cellulose in cell walls, which is the most abundant carbohydrate.In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is partially stored as a polymer, in plants mainly as starch and amylopectin and in animals as glycogen. Glucose circulates in the... Read More

Endocrine System

Image The endocrine system is a chemical messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. In humans, the major endocrine glands are the thyroid gland and the adrenal glands. In vertebrates, the hypothalamus is the neural control center for all endocrine systems. The study of the endocrine system and its disorders is known as endocrinology. Endocrinology is a branch of internal medicine. A number of glands that signal each other in sequence are usually referred to ... Read More

Diabeteess

Image Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time Symptoms often include frequent urination, increased thirst, and increased hunger. If left untreated, diabetes can cause many complications.Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death.Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes and cognitive impairment. Diabetes is d... Read More

Blood Sugar Level

Image The blood sugar level, blood sugar concentration, or blood glucose level is the concentration of glucose present in the blood of humans and other animals. Glucose is a simple sugar and approximately 4 grams of glucose are present in the blood of a 70-kilogram (150 lb) human at all times.The body tightly regulates blood glucose levels as a part of metabolic homeostasis.Glucose is stored in skeletal muscle and liver cells in the form of glycogen;in fasted individuals, blood glucose is maintained at a constant level at the expense of glycogen stores in the liver and skeletal muscle. ... Read More

Let the World know about your Opinions

Image Otology and Rhinology is creating a platform for publishing the justifiable opinions of the related to all the inconveniences of ENT in relation to the nCovid-19 with a single blind review. Such that these opinions may come in handy while working various elements of the prevention of ncovid-19. Your submissions are welcomed through online at https://www.scholarscentral.org/submissions/otology-rhinology.html or as an email attachment to otol.rhinol@emedsi.com at your e... Read More

Urinary incontinence in injured women.

Image Urinary incontinence (UI), known also as excessive urination, is any spontaneous urinary leakage. It is a serious and distressing condition that can have a significant effect on quality of life. This has been recognized as an important concern in geriatric health care. The word enuresis is also used mainly in children to refer to urinary incontinence, such as nocturnal enuresis (bed wetting). Big risk factors include pelvic surgery, pregnancy, childbirth and menopause. Urinary incontinence is frequently the product of an underlying medical condition that is unreported to medical practitione... Read More

Lung Transplantation

Image Lung diseases like Chronic obstructive pulmonary disease, Idiopathic pulmonary fibrosis, Cystic fibrosis, Idiopathic pulmonary arterial hypertension are resulting as a death prone inconveniences. There is no other alternative than lung transplantation to increase the lifespan. But this transplantation is a very complicated and comprises of several complications You are welcomed to share your opinions or submissions through online at https://www.scholarscentral.org/submissions/archives-transplantation.html... Read More

Dup15 Q syndrome

Image Dup15q syndrome is the common name for chromosome 15q11.2-q13.1 duplication syndrome. This is a neurodevelopmental disorder, caused by the partial duplication of Chromosome 15, that confers a strong risk for autism spectrum disorder, epilepsy, and intellectual disability.It is the most common genetic cause of autism, accounting for approximately 1-3% of cases.Dup15q syndrome includes both interstitial duplications and isodicentric duplications. Dup15q syndrome is caused by copy number variation (CNV) in which extra copies of certain genes ar... Read More

Angelman syndrome

Image Angelman syndrome (AS) is a genetic disorder that mainly affects the nervous system. Angelman syndrome is due to a lack of function of part of chromosome 15 inherited from a person's mother. Most of the time, it is due to a deletion or mutation of the UBE3A gene on that chromosome. Occasionally, it is due to inheriting two copies of chromosome 15 from a person's father and none from their mother. As the father's versions are inactivated by a process known as genomic imprinting, no functional version of the gene rem... Read More

Thiocyanate Blood Levels in Chlorobenzylidenemalononitrile (CS) Riot Control Gas Patients;the Egyptian Experience

Image This study aims to clarify the systemic toxic effects of chlorobenzylidenemalononitrile (CS) and to confirm or reject the possibility of cyanide intoxication on the exposed patients. The study was conducted in PCC Ain Shams University, on exposed rioters during the November 2011 demonstrations to CS gas in Cairo. Control groups included light and moderate to heavy smokers as well as non-smokers. Plasma thiocyanate, the metabolite of cyanide was assayed in all groups. Plasma thiocyanate of victims of CS exposed gas showed no significant differences from light smoker volunteers and was not si... Read More

The Sterol Regulatory Element Binding Transcription Factor 1 (SREBP1): An Attractive Therapeutic Target in CNS Drug Discoveries

Image Sterol regulatory element binding proteins (SREBPs) are endoplasmic reticulum (ER) residing transcription factors best known for their roles in regulation of genes mostly involved in the lipid biogenesis and metabolism in the liver and adipose tissues. This family of lipid transcription factors consists of SREBP1a, SREBP1c, and SREBP2. Sterol regulatory element binding proteins (SREBPs) are endoplasmic reticulum (ER) residing transcription factors best known for their roles in regulation of genes mostly involved in the lipid biogenesis and metabolism in the liver and adipose tissues. This f... Read More

An Unusual Homicide Involving Strangulation after Transdermal Fentanyl and Buprenorphine Intoxication

Image Fentanyl and buprenorphine are powerful opioids used for the induction of anesthesia as well as for severe pain management.Transdermal fentanyl and buprenorphine patches are widely used for outpatient management of chronic pain. However several cases of deaths connected with their administration have been described in literature. We present an unusual and exceptional homicidal death attributed to a combination system of acute transdermal opioids poisoning and strangulation. The concentration of the drugs and their metabolites in femoral blood and urine were capable of causing fatal intoxica... Read More

YOGA AS A THERAPEUTIC INTERVENTION : A BIBLIOMETRIC ANALYSIS OF PUBLISHED RESEARCH STUDIES

Image The Journal focuses on yoga, meditation, pranayama, asana, and bibliometric mind-body medicine. Although yoga is historically a spiritual discipline, it has also been used clinically as a therapeutic intervention. A bibliometric analysis on the biomedical journal literature involving research on the clinical application of yoga has revealed an increase in publication frequency over the past 3 decades with a substantial and growing use of randomized controlled trials. Types of medical conditions have included psychopathological (e.g. depression, anxiety), cardiovascular (e.g. hypertensi... Read More

Endoplasmic Reticulum Stress and Related Pathological Processes

Image The endoplasmic reticulum (ER) plays a pivotal role in lipid and protein biosynthesis as well as calcium store regulation, which determines its essential role in cell function. Hypoxia, nutrient deprivation, perturbation of redox status and aberrant calcium regulation can all trigger the ER stress response, which is mediated through three main sensors, namely inositol requiring element-1 (IRE-1), protein kinase-like ER kinase (PERK) and activating transcription factor 6 (ATF6). This review explores the interaction of ER stress and ER stress-associated pathological processes, including infla... Read More

Hatha Yoga Therapy Management of Urologic Disorders

Image Hatha Yoga (often referred to “yoga”) is an ancient type of physical and mental exercise that has been used as a therapeutic modality in traditional Indian medicine for centuries. Yoga as a complementary modality in western medicine is more recent and continues to grow. Chronic urologic disorders are often difficult to diagnose because their presentation mimic other medical conditions and are often a diagnosis of exclusion. Treatment is also frustrating because the more traditional treatments are often unsuccessful in managing chronic disorders. Health care practitioners are oft... Read More

Transient elastography: a meta-analysis of diagnostic accuracy in evaluation of portal hypertension in chronic liver disease

Image The Journal focuses on diagnostic accuracy, portal hypertension, sensitivity, specificity, and transient elastography.Transient elastography (TE), as a non-invasive method, has been studied for evaluation of portal hypertension in patients with chronic liver diseases (CLD) with variable results. We studied the performance of TE for detection of significant portal hypertension, oesophageal varices and large oesophageal varices using meta-analysis. Methods: PubMed, the Cochrane Library, EMBASE and ISI web of Knowledge were searched. The studies published in English relating to the diag... Read More

Nonalcoholic Fatty Liver Disease

Image The Journal focuses on  Steatosis, Nonalcoholic steatohepatitis, Insulin resistance, Ursodeoxycholic acid, and Betaine. Nonalcoholic fatty liver disease (NAFLD) encompasses a broad clinicopathologic spectrum ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), which may advance to cirrhosis and end-stage liver disease. Steatosis alone does not appear to be progressive. The prevalence of NAFLD averages 20% and that of NASH, 2% to 3%, making these conditions the most common liver diseases in the United States. NAFLD is associated with insulin resistance, which ... Read More

Drug Metabolism and Pharmacokinetics, the Blood-Brain Barrier, and Central Nervous System Drug Discovery

Image The Journal focuses on Blood-brain barrier, CNS drug discovery, DMPK, pharmacokinetics, pharmacodynamics, microdialysis, MDCK cells, in silico prediction of brain permeation, aging, and brain disorders.The worldwide market for therapies for CNS disorders is worth more than $50 billion and is set to grow substantially in the years ahead. This is because: 1) the incidence of many CNS disorders (e.g., Alzheimer’s disease, stroke, and Parkinson’s disease) increase exponentially after age 65 and 2) the number of people in the world over 65 is about to increase sharply because of a ma... Read More

EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCE

Image The intrinsic clearances (CLint) of 50 neutral and basic marketed drugs were determined in fresh human hepatocytes and the data used to predict human in vivo hepatic metabolic clearance (CLmet). A statistically significant correlation between scaled CLmet and actual CLmet was observed (r2  0.48, p < 0.05), and for 73% of the drugs studied,scaledclearanceswerewithin2-foldoftheactualclearance. These data have shown that CLint data generated in human hepatocytes can be used to provide estimates of human hepatic CLmet for both phase I and phase II processes. In addition, the utility of comm... Read More

Cervical pain cause and Treatment.

Image Neck pain may have causes not related to underlying illness. Examples include excessive straining (looking up or down), uncomfortable sleeping, pain, chiropractic manipulation or heavy jewelry wear. Cervical pain is the discomfort caused by cervical or osteoarthritis spondylolysis or. This disorder involves changes in the neck-connected bones, discs or joints. The main causes of cervical pain are due to the wear and tear of cartilages and bones, and are most frequently seen in aging individuals. Submit your submission here https://www.scitechnol.com/submission/ Check website for more detail... Read More

Journal of Otology Rhinology

Image Journal of Otology & Rhinology (JOR) is a hybrid open access international journal which is distributed all over the globe. The Journal focuses on audiology, speech therapy, oral and neck oncology, neurotology, otolaryngology and Sleep Apnea disorders. Otology is a branch of medicine which studies normal and pathological anatomy and physiology of the ear (hearing and vestibular sensory systems and related structures and functions) as well as their diseases, diagnosis and treatment. Rhinology refers to a subspecialty within the field of otolaryngology (ENT) focused on the t... Read More

Awareness and knowledge of physical therapy among adult populations in Saudi Arabia.

Image The aim of this study is to ascertain general public awareness and knowledge of physiotherapy in the Kingdom of Saudi Arabia. The authors built a cross-sectional sample using an auto-administered questionnaire. The research was conducted between June and August 2018 where the questionnaire was planted online and invitation to participate in the research along with an description of its significance, and a link to the questionnaire was sent to individuals via various social media platforms. To know more follow https://www.scitechnol.com/peer-review/awareness-and-knowledge-of-physical-therapy... Read More

Pharmaceuticals in the Environment

Image The Journal focuses on effects, fate, green pharmacy, occurrence, risk, sustainable pharmacy.Pharmaceuticalsarechemicalsthatareusedbecauseoftheirbiological activity.Theyareoftenexcretedunchangedandcanreachtheenvironment. Throughout developed countries, the pharmaceutical concentrations in the aquatic environment are in the same range (μgL −1 and below); however, it is not clear whether this holds for less-developed countries too. The health risks of active pharmaceutical ingredients (APIs)remainpoorlyunderstood.Althoughtherearenoknownshorttermeffectsonhumans,long-termeffectsca... Read More

Fluorine in Pharmaceuticals: Looking Beyond Intuition

Image Fluorine substituents have become a widespread and important drug component, their introduction facilitated by the development of safe and selective fluorinating agents. Organofluorine affects nearly all physical and adsorption, distribution, metabolism, and excretion properties of a lead compound. Its inductive effects are relatively well understood, enhancing bioavailability, for example, by reducing the basicity of neighboring amines. In contrast, exploration of the specific influence of carbon-fluorine single bonds on docking interactions, whether through direct contact with the protein... Read More

Biology of Gastrointestinal Stromal Tumors

Image Once a poorly defined pathologic oddity, in recent years, gastrointestinal stromal tumor (GIST) has emerged as a distinct oncogenetic entity that is now center stage in clinical trials of kinase-targeted therapies. This review charts the rapid progress that has established GIST as a model for understanding the role of oncogenic kinase mutations in human tumorigenesis. Approximately 80% to 85% of GISTs harbor activating mutations of the KIT tyrosine kinase. In a series of 322 GISTs (including 140 previously published cases) studied by the authors in detail, mutations in the KIT gene occurre... Read More

Childhood functional gastrointestinal disorders

Image The Journal focuses on  infant vomiting, cyclic vomiting syndrome, functional dyspepsia in children, irritable bowel syndrome in children, functional abdominal pain in children, functional diarrhea in children, functional constipation in children, and Rome II.This is the first attempt at defining criteriaforfunctionalgastrointestinaldisorders (FGIDs) in infancy,childhood,and adolescence. The decision-making process was as for adults and consisted of arriving at consensus, based on clinical experience. This paper is intended to be a quick reference. The classification system sel... Read More

Codeine

Image Codeine Codeine is an opiate used to treat pain, coughing, and diarrhea.It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen.Evidence does not support its use for acute cough suppression in children or adults.In Europe, it is not recommended as a cough medicine in those under 12 years of age.It is generally taken by mouth. It typically starts working after half an hour, with maximum effect at two hours. ... Read More

MORPHIINE

Image MORPHIINE Morphine is a pain medication of the opiate family which is found naturally in a number of plants and animals, including humans. It acts directly on the central nervous system (CNS) to decrease the feeling of pain. It can be taken for both acute pain and chronic pain.[6] It is frequently used for pain from myocardial infarction and during labor.[6] It can be given by mouth, by injection into a muscle, by injection under the skin, intravenously, injection into the space around the spinal cord, or rectally.Maximum effect is reached after about 20 minu... Read More

Meditation States and Traits: EEG, ERP, and Neuroimaging Studies

Image Neuroelectric and imaging studies of meditation are reviewed. Electroencephalographic measures indi￾cate an overall slowing subsequent to meditation, with theta and alpha activation related to proficiency of practice. Sensory evoked potential assessment of concentrative meditation yields amplitude and latency changes for some components and practices. Cognitive event-related potential evaluation of  meditation implies that practice changes attentional allocation. Neuroimaging studies indicate increased regional cerebral blood flow measures during meditation. Taken to... Read More

EXTRACTION, ISOLATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS FROM PLANTS’ EXTRACTS

Image The Journal focuses on Bioactive compound, Plant Extraction, Isolation, Herbal preparations, and Natural products.Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, interest particularly in edible plants has grown throughout the world. Botanicals and herbal preparations for medicinal usage contain various type... Read More

Pacemakers for Children

Image A permanent pacemaker is a small device that is implanted under the skin and sends electrical signals to start or regulate a slow heartbeat.  A permanent pacemaker may be used to stimulate the heartbeat if the heart's natural pacemaker (the sinoatrial, or SA, node) is not functioning properly, has developed an abnormal heart rate or rhythm, or if the electrical pathways are blocked. Children's pacemakers may be placed under the skin in one of several locations. Young children (infants, toddler, preschool, and young school-aged children) often have the pacema... Read More

Narcotics

Image Narcotics The term narcotic originally referred medically to any psychoactive compound with sleep-inducing properties, and euphoric properties as well. In the United States, it has since become associated with opiates and opioids, commonly morphine and heroin, as well as derivatives of many of the compounds found within raw opium latex. The primary three are morphine, codeine, and thebaine (while thebaine itself is only very mildly psychoactive, it is a crucial precursor in the vast ma... Read More

ANESTHETIZED

Image ANESTHETIZED Anesthesia or anaesthesia (from Greek "without sensation") is a state of controlled, temporary loss of sensation or awareness that is induced for medical purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. A patient under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of medical procedu... Read More

Bleeding Diathesis

Image In medicine bleeding diathesis is an unusual susceptibility to bleed mostly due to hypocoagulability (a condition of irregular and slow blood clotting), in turn caused by a coagulopathy (a defect in the system of coagulation). Therefore, this may result in the reduction of platelets being produced and leads to excessive bleeding. Several types of coagulopathy are distinguished, ranging from mild to lethal. Coagulopathy can be caused by thinning of the... Read More

Transfusion

Image Transfusion medicine is the branch of medicine that encompasses all aspects of the transfusion of blood and blood components including aspects related to hemovigilance. It includes issues of blood donation, immunohematology and other laboratory testing for transfusion-transmitted diseases, management and monitoring of clinical transfusion practices, patient blood management, therapeutic apheresis, stem cell collections, cellular therapy, and coagulati... Read More

Myeloma

Image Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, bleeding, frequent infections, and anaemia may occur. Complications may include amyloidosis. Multiple myeloma is considered treatable, but generally incurable. Remissions may be brought about with steroids, chemotherapy, targeted ... Read More

Circulatory System

Image The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis. The circulatory system includes the lymphatic syst... Read More

Hematopoietic stem cell transplantation

Image Hematopoietic stem cell transplantation is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myelom... Read More

Coagulation

Image Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanism of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. The coagulation cascade of secondary hemostasis has two initial pathways which... Read More

Thrombosis

Image Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around t... Read More

Leukemia

Image Leukemia, also spelled leukaemia, is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Symptoms may include bleeding and bruising, feeling tired, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow b... Read More

Heart Transplantation in Children

Image What Is a Heart Transplant? A heart transplant is a surgery in which doctors remove a person's sick heart and replace it with a healthy donor heart. Transplants are done when a child's heart does not work well and he or she won't survive without a new one. Doctors sometimes call this heart failure, or end-stage pediatric heart disease. They usually first try to treat heart fai... Read More

Congenital Heart Defects

Image Congenital heart defects (CHDs) are the most common type of birth defect. As medical care and treatment have advanced, babies with a CHD are living longer and healthier lives. Learn more facts about CHDs below. CHDs are present at birth and can affect the structure of a baby’s heart and the way it works. They can affect how blood flows through the heart and out to the rest of the body. CHDs can vary from mild (such as a small hole in the heart) to severe (such as missing or poorly formed parts of the heart).... Read More

Atherosclerosis

Image What Is Atherosclerosis is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body. Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death. Major Risk Fact... Read More

Virology

Image Virology is the study of viral – submicroscopic, parasitic particles of genetic material contained in a protein coat and virus-like agents. It focuses on the following aspects of viruses: their structure, classification and evolution, their ways to infect and exploit host cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. Virology is considered to be a subfield of microbiology or of medicine. A major branch of virology is virus classi... Read More

Unicellular

Image A unicellular organism, also known as a single-celled organism, is an organism that consists of a single cell, unlike a multicellular organism that consists of multiple cells. Unicellular organisms fall into two general categories: prokaryotic organisms and eukaryotic organisms. Prokaryotes include bacteria and archaea. Many eukaryotes are multicellular, but the group includes the protozoa, unicellular algae, and unicellular fungi. Unicellular organisms are thought to be the oldest form of life, with early protocells possibly emerging 3.8–4 billion years ago Although some pr... Read More

THE STUDY OF ARCHAEA

Image Archaeal cells have unique properties separating them from the other two domains, Bacteria and Eukaryota. Archaea are further divided into multiple recognized phyla. Classification is difficult because most have not been isolated in the laboratory and have only been detected by analysis of their nucleic acids in samples from their environment. Archaea and bacteria are generally similar in size and shape, although a few archaea have very different shapes, such as the flat and square cells of Haloquadratum walsbyi. Despite this morphological similarity to bacteria, archaea possess g... Read More

Multicellular

Image Multicellular organisms are organisms that consist of more than one cell, in contrast to unicellular organisms. All species of animals, land plants and most fungi are multicellular, as are many algae, whereas a few organisms are partially uni- and partially multicellular, like slime molds and social amoebae such as the genus Dictyostelium All species of animals, land plants and most fungi are multicellular, as are many algae, whereas a few organisms are partially uni- and partially multicellular, like slime molds and social amoebae such as the genus Dictyostelium You can... Read More

Microorganisms

Image Microorganisms include all unicellular organisms and so are extremely diverse. Of the three domains of life identified by Carl Woese, all of the Archaea and Bacteria are microorganisms. These were previously grouped together in the two domain system as Prokaryotes, the other being the eukaryotes. The third domain Eukaryota includes all multicellular organisms and many unicellular protists and protozoans. Some protists are related to animals and some to green plants. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks and the deep sea. Some are ... Read More

Fungi

Image characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Similar to animals, fungi are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related orga... Read More

Osteoporosis

Image Osteoporosis is a disease in which bone weakening increases the risk of a broken bone. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor s... Read More

Insulin

Image Insulin  is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of carbohydrates, especially glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in t... Read More

Thyroid gland

Image The thyroid, or thyroid gland, is an endocrine gland in the neck consisting of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the thyroid isthmus. The thyroid is located at the front of the neck, below the Adam's apple. Microscopically, the functional unit of the thyroid gland is the spherical thyroid follicle, lined with follicular cells, and occasional Para follicular cells that surround a lumen containing ... Read More

Overweight

Image Obesity is a medical condition in which excess body fat has accumulated to an extent that it may have a negative effect on health. People are generally considered obese when their body mass index (BMI), a measurement obtained by dividing a person's weight by the square of the person's height, is over 30 kg/m2; the range 25–30 kg/m2 is defined as overweight. Some East Asian countries use lower values. Obesity is most commonly caused by a combi... Read More

Hormones

Image A hormone is any member of a class of signaling molecules, produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behavior. Hormones serve to communicate between organs and tissues for physiological regulation and behavioral activities such as digestion, metabolism, respiration, tissue function, sensory perception, sleep, excretion, lactation, stress induction, growth and devel... Read More

Diabetes

Image Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Symptoms often include frequent urination, increased thirst, and increased hunger. If left untreated, diabetes can cause many complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or d... Read More

Hyperglycemia

Image Hyperglycemia is a condition in which an excessive amount of glucose circulates in the blood plasma. This is generally a blood sugar level higher than 11.1 mmol/l (200 mg/dl). For diabetics, glucose levels that are considered to be too hyperglycemic can vary from person to person, mainly due to the person's renal threshold of glucose and overall glucose tolerance. The degree of hyperglycemia can ch... Read More

Endocrine glands

Image Endocrine glands  Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood. The major glands of the endocrine system include the pineal gland, pituitary gland, pancreas, ovaries, testes, thyroid gland, parathyroid gland, hypothalamus and adrenal glands. The pituitary gla... Read More

Systematic Tissue Specific Approach for Examination and Conservative Management of Shoulder Pain.

Image The use of examination procedures to identify specific tissue involvement in painful conditions is a critical element in musculoskeletal physical therapy practice. Physical therapists can benefit from this approach to patient examination because it allows them to focus treatments on the specific causes of symptoms. The purpose of this case study is to describe a systematic approach to examination and treatment of shoulder pain through the identification of specific pain generators. The patient presented in this case had a five month onset of left anteriolateral shoulder pain. Based on the e... Read More

Atrial septal defect in symptomatic children weighing ≤10 kg.

Image Atrial septal defect (ASD) Atrial sepal defect (ASD) constitutes 8%–10% of the congenital heart defects in children. The secundum ASD accounts for nearly 75% of all ASDs. Since the introduction of transcatheter device closure for secundum ASDs  there has been a paradigm shift in their management. Over the years, the procedure has evolved significantly to become a treatment of choice in many institutions. The Amplatzer septal occluder (ASO) is the most widely used device owing to its user-friendliness and high success rate. You can ... Read More

Types of sports injuries

Image Sports injuries occur during exercise or while participating in a sport. Children are particularly at risk for these types of injuries, but adults can get them, too. Different sports injuries produce different symptoms and complications. The most common types of sports injuries include: Sprains: Overstretching or tearing the ligaments results in a sprain. Ligaments are pieces of tissue that connect two bones to one another in a joint. Strains: Overstretching or tearing muscles or tendons results in a sprain. Tendons are thick, fibrous cords of tissue that connect bone to muscle. Strains are... Read More

Study of Chondroplasty

Image Chondroplasty is a surgical procedure used to smooth damaged cartilage in the knee. The goal of the surgery is to lessen friction in the joint, allowing the knee to move freely and without pain. The knee joint is covered in articular cartilage, which is a smooth tissue that allows the joint to move without friction. Trauma and degenerative conditions can damage the cartilage and cause it to become rough. Studies have found that the majority of patients who undergo chondroplasty are satisfied with the results of the procedure. Chondroplasty is done arthroscopically. This means that a thin in... Read More

Study of Musculoskeletal System

Image The skeletal system includes the bones of the skeleton and the cartilages, ligaments, and other connective tissue that stabilize or connect the bones. In addition to supporting the weight of the body, bones work together with muscles to maintain body position and to produce controlled, precise movements. Without the skeleton to pull against, contracting muscle fibers could not make us sit, stand, walk, or run. The skeletal system includes the bones of the skeleton and the cartilages, ligaments, and other connective tissue that stabilize or connect the bones. In addition to supporting the we... Read More

Study of Orthopedic Trauma

Image Orthopedic trauma is a broad term describing all kinds of injuries affecting the bones, joints, muscles, tendons, and ligaments in any part of the body that are caused by trauma. The term is wide-ranging and may refer to minor fractures or severely broken bones with a direct threat to the patient’s life. It is considered as a sub-specialty of orthopaedic surgery and is focused on treating fractured bones and making sure the injured part of the body regains its original strength and maximum function it used to have prior to the injury. Minor injuries are sometimes difficult to treat, a... Read More

SPINE DISORDERS

Image There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time. Some of the common cervical spine diseases include degenerative disc disease, cervical stenosis, and cervical disc herniation. Degenerative disc disease occurs over time when the discs within each vertebra in the neck begin to fall apart and begin to disi... Read More

FRACTURE

Image A fracture is the medical term for a broken bone.Fractures are common, The average person has two during a lifetime. They occur when the physical force exerted on the bone is stronger than the bone itself. Your risk of fracture depends, in part, on your age. Broken bones are very common in childhood, although children's fractures are generally less complicated than fractures in adults. As you age, your bones become more brittle and you are more likely to suffer fractures from falls that would not occur when you were young. There are many types of fractures, but the main categories are d... Read More

Rheumatoid

Image Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Autoimmune diseases are illnesses that occur when the body's tissues are mistakenly attacked by their own immune system. The immune system contains a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with autoimmune diseases have antibodies and immune cells in their blood that target their own body tissues, where they can be associated with inflammation. While joint tissue inflammation and ... Read More

What is osteoarthritis

Image Osteoarthritis (OA) is the most common chronic (long-lasting) joint condition.A joint is where two bones come together. The ends of these bones are covered with protective tissue called cartilage. With OA, this cartilage breaks down, causing the bones within the joint to rub together. This can cause pain, stiffness, and other symptoms.OA occurs most often in older people, although it can occur in adults of any age. OA is also called degenerative joint disease, degenerative arthritis, and wear-and-tear arthritis.A leading cause of disability, OA affects more than 30 million men and womenTrus... Read More

Gluten Introduction and the Risk of Coeliac Disease: A Position Paper by the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition

Image The Journal focuses on children, coeliac disease, gluten, infant feeding, nutrition, and recommendations. The objective is to provide updated recommendations regarding gluten introduction in infants and the risk of developing coeliac disease (CD) during childhood. The risk of inducing CD through a gluten-containing diet exclusively applies to persons carrying at least one of the CD risk alleles. Because genetic risk alleles are generally not known in an infant at the ... Read More

Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition

Image The Journal focuses on biliary atresia, hepatoportoenterostomy, Kasai, liver biopsy, neonatal cholestasis, neonatal jaundice, and radionuclide scan. Cholestatic jaundice in infancy affects approximately 1 in every 2500 term infants and is infrequently recognized by primary providers in the setting of physiologic jaundice. Cholestatic jaundice is always pathologic and indicates hepatobiliary dysfunction. Early detection by the primary care physician and timely referral... Read More

Measuring Mindfulness in Insight Meditation (Vipassana) and Meditation-Based Psychotherapy: The Development of the Freiburg Mindfulness Inventory (FMI) by Nina Buchheld1, Paul Grossman2 and HaraldWalach3

Image The Journal focuses on Mindfulness Meditation, Insight Meditation, Vipassana, Measurement Instrument, Questionnaire, and Assessment. Mindfulness meditation research has in recent years become a burgeoning field of investigation, particularly related to treatment of health-related disorders. Nevertheless, the construct of mindfulness has not yet been subjected to scientific validation. The aim of this study has been the empirical analysis of the Buddhist concept of mindful... Read More

Loving-Kindness Meditation Increases Social Connectedness

Image The Journal focuses on meditation, compassion, prosocial emotion, emotion regulation, implicit affect. Meditation is a practice where an individual uses a technique – such as mindfulness, or focusing the mind on a particular object, thought, or activity – to train attention and awareness, and achieve a mentally clear and emotionally calm and stable state. Compassion motivates people to go out of their way to help the physical, mental, or emotional pains of ano... Read More

Dissociatives

Image Dissociatives Dissociatives are a class of hallucinogen which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self. This is done through reducing or blocking signals to the conscious mind from other parts of the brain.Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they produce hallucinogenic effects, which may include sensory deprivation, dissociation,&... Read More

Cannabis

Image Cannabis Cannabis, also known as marijuana among other names, is a psychoactive drug from the Cannabis plant used for medical or recreational purposes. The primary psychoactive component of cannabis is tetrahydrocannabinol (THC), one of the 483 known compounds in the plant, including at least 65 other cannabinoids. Cannabis can be used by smoking, vaporizing, within food, or as an extract. Cannabis has mental and physical effects. It causes a hig... Read More

Echocardiogram

Image An echocardiogram uses sound waves to produce images of your heart. This common test allows your doctor to see your heart beating and pumping blood. Your doctor can use the images from an echocardiogram to identify heart disease. Depending on what information your doctor needs, you may have one of several types of echocardiograms. Each type of echocardiogram involves few, if any, risks. Transthoracic echocardiogram In this standard type of echocardiogram: A technician (sonographer) spreads gel on a device (transducer). ... Read More

Role of Cell Injections in Decreasing the Rejection of a Transplanted Organ

Image Transplants can be life-saving, but to stop the donor organ being rejected by the recipient’s immune system, people have to take several drugs that have serious side. A study reported that, a one-off injection of cells could be a long-sought solution to the problem of the body rejecting an organ transplant. We look forward to hear your opinions and views on this topic at transplant@scitecjournals.com. Please feel free to share your views and opinions at to make the people aware of the medical facts. For more details go ... Read More

Cleft Palate Surgery Made Easy by Distraction Osteogenesis

Image A procedure that uses the mechanical force of an appliance to lengthen soft tissue and bone, may be a feasible and effective method to repair cleft palate in the future. More suggestions or discussion in detail of this topic is welcomed at the journal office at otorhino@peerjournal.org. Kindly, browse through the link provided below for more updates regarding the journal. https://www.scitechnol.com/otology-rhinology.php ... Read More

Cure of Scheurmann’s Disease in an Adult Male by checking Effect of Conservative Treatment with Physiotherapy.

Image Scheuermann’s Disease is the developmental disorder of spine in which wedge shaped vertebrae of thoracic spine are found which leads to excessive curvature and postural abnormality that causes stiffness and pain in upper back and later compromise of respiratory functions and disability occurs. For investigation of the effect of spinal mobilization, breathing exercise and home exercises in an adolescent with Scheuermann’s Disease. The study was done on a 17 years old boy with the complaint of severe low back pain. An exercise program was given for 45 minutes for 8 weeks which inc... Read More

For Ischemic Stroke patient, use of ICF in physiotherapy management: A case study.

Image Globally, CVA is the most common cause of disability and death. Each year approximately 5.5 million people are killed by stroke. In Bangladesh stroke is the ‘third’ leading causes of death. Physiotherapy management is evidence-based treatment approach that has short-term and long-term effect on functional outcome in patients with CVA. The ICF play an important role in functioning and health for patient with stroke. A case-based study was conducted. The problem was found by implementing International Classification of Functioning, Disability and Health (ICF).... Read More

Misdiagnosis of Tonsil Malignant Lymphoma

Image The study filed that the clinical data of one patient who was misdiagnosed as chronic tonsillitis and finally diagnosed as malignant lymphoma of tonsil was analysed retrospectively to summarize and reflect on the clinical manifestations, diagnosis and treatment of malignant lymphoma of tonsil, so as to improve the clinical understanding and diagnosis of this disease. It has been reported that the misdiagnosis rate of malignant lymphoma of tonsil is quite high, up to 41.3%.   On this note the Journal of Otology and Rhinology wants to hear out your opinions about the ... Read More

Genetic Drift

Image Genetic Drift Genetic drift (also known as allelic drift or the Sewall Wright effect) is the change in the frequency of an existing gene variant (allele) in a population due to random sampling of organisms. The alleles in the offspring are a sample of those in the parents, and chance has a role in determining whether a given individual survives and reproduces. A population's allele frequency is the fraction of the copies of one gene that share a particular form. Genetic drift may cause gene variants to di... Read More

The Italian Society of Gastroenterology (SIGE) and the Italian Group for the study of Inflammatory Bowel Disease (IG-IBD) Clinical Practice Guidelines: The use of tumor necrosis factor-alpha antagonist therapy in Inflammatory Bowel Disease

Image The Journal focuses on Biologics, Guidelines, Inflammatory Bowel Disease, and Tumor necrosis factor-alpha antagonist. A biologic drug (biologics) is a product that is produced from living organisms or contains components of living organisms. Inflammatory bowel disease (IBD) is an umbrella term used to describe disorders that involve chronic inflammation of your digestive tract. A Tumor necrosis factor (TNF) inhibitor is a pharmaceutical drug that suppresses the physio... Read More

Aceology

Image Aceology Treatment and therapy are generally considered synonyms. However, in the context of mental health, the term therapy may refer specifically to psychotherapy. The words care, therapy, treatment, and intervention overlap in a semantic field, and thus they can be synonymous depending on context. Moving rightward through that order, the connotative level of holism decreases and the level of specificity (to concrete instances) increases. Thus,... Read More

Recommendations on the use of Biosimilars by the Brazilian Society of Rheumatology, Brazilian Society of Dermatology, Brazilian Federation of Gastroenterology and Brazilian Study Group on Inflammatory Bowel Disease—Focus on clinical evaluation of monoclonal antibodies and fusion proteins used in the treatment of autoimmune diseases

Image The Journal focuses on Biosimilars, Autoimmune diseases, Rheumatoid arthritis, Ankylosing spondylitis, Psoriasis, and Crohn's disease. Biosimilars are approved according to the same standards of pharmaceutical quality, safety and efficacy that apply to all biological medicines. An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. Rheumatoid arthritis (RA) is an autoimmune disease that can cause joint pain and damage ... Read More

Medical Yoga Therapy

Image The Journal focuses on yoga, yogic practice, anxiety, depression, mindfulness, meditation, arthritis, ADHD, cardiovascular disease, and inflammation. Yoga is a group of physical, mental, and spiritual practices or disciplines which originated in ancient India. Yoga is a systematic practice of physical exercise, breath control, relaxation, diet control, and positive thinking and meditation aimed at developing harmony in the body, mind, and environment. ... Read More

opioids

Image Opioids Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia.Other medical uses include suppression of diarrhea, replacement therapy for opioid use disorder, reversing opioid overdose, suppressing cough,as well as for executions in the United States. Extremely potent opioids such as carfentanil are approved only for veterinary use. Opioids are also frequently used non-medically for their ... Read More

Hallucinogens

Image Hallucinogens A hallucinogen is a psychoactive agent which most likely causes hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness. The common types of hallucinogens are psychedelics, dissociatives and deliriants. Although hallucinations are a common symptom of amphetamine psychosis, amphetamines are not considered hallucinogens as they are not a primary effect of the drugs themselves. While hallucinations can occur when abus... Read More

Osteoarthritis

Image Osteoarthritis such topics are published in Journal of Physiotherapy and Rehabilitationis which is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a "cushion" between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common joint disease. OA occurs more frequently as we age. Before age 45, ... Read More

Rheumatoid Arthritis

Image Rheumatoid arthritis (RA) is the most common type of autoimmune arthritis. It is caused when the immune system (the body’s defense system) is not working properly. RA causes pain and swelling in the wrist and small joints of the hand and feet. Treatments for RA can stop joint pain and swelling. Treatment also prevents joint damage. Early treatment will give better long term results. Regular low-impact exercises, such as walking, and exercises can increase muscle strength. This will improve your overall health and lower pressure on your joints. Studies sho... Read More

Levamisole in Gastric Content after Unusual Intake of Heroin and Cocaine

Image Levamisole is an antibiotic medication used to treat colon cancer and is a synthetic imidazothiazole derivative also employed as an antihelminthic to treat worm infestations in both humans and animals. Even if it is not yet well known why levamisole is added to cocaine, the presence of this adulterant is very dangerous, in fact this compound suppresses the production of white blood cells, resulting in neutropenia, agranulocytosis and idiopathic pulmonary hypertension. With the increasing use of levamisole as an adulterant, a number of these complications have been reported among cocaine use... Read More

Smoking Marijuana, Is it Safe for the Heart?

Image Different preparations of Cannabis sativa (commonly marijuana and hashish) are widely used mainly for their euphoric effects. Cannabis after alcohol consumption is by far the most commonly used recreational drug in Europe. About 20% of adults in the European Union (aged 15-64 years), over 62 million people, have tried cannabis at least once in their life . Users and lay people believe that marijuana or hashish is safe. Many cases of cardiovascular events have, however, been related to a cannabis consumption, and cases of acute ischemia or thrombosis even on the ground of normal coronary art... Read More

Effects of Aqueous Extract of Phyllanthus muellerianus Leaves on Castor Oil-induced Diarrhoeal Rats

Image Cancer is one of the leading causes of death and globally the numbers of cases of cancer are increasing gradually. There are several medicines available in the market to treat the various types of cancer but no drug is found to be fully effective and safe. The major problem in the cancer chemotherapy is the toxicity of the established drugs. However plants and plant derived products have proved effective and safe in the treatment and management of cancers. These days most of the research work on cancer drugs is targeted on plants and plants derived natural products. Many natural products an... Read More

Anticancer Potential of Plants and Natural Products:

Image Cancer is one of the leading causes of death and globally the numbers of cases of cancer are increasing gradually. There are several medicines available in the market to treat the various types of cancer but no drug is found to be fully effective and safe. The major problem in the cancer chemotherapy is the toxicity of the established drugs. However plants and plant derived products have proved effective and safe in the treatment and management of cancers. These days most of the research work on cancer drugs is targeted on plants and plants derived natural products. Many natural products an... Read More

Antiaging Creams

Image Anti-aging creams are predominantly moisturiser-based cosmeceutical skin care products marketed with the promise of making the consumer look younger by reducing, masking or preventing signs of skin aging. These signs are laxity (sagging), rhytids (wrinkles), and photoaging, which includes erythema (redness), dyspigmentation (brown discolorations), solar elastosis (yellowing), keratoses (abnormal growths), and poor texture, common ingredients in ... Read More

Growth hormone deficiency

Image Growth hormone deficiency (GHD) is a rare disorder characterized by the inadequate secretion of growth hormone (GH) from the anterior pituitary gland, a small gland located at the base of the brain that is responsible for the production of several hormones. The most common treatment for growth hormone deficiency in both children and adults is growth hormone therapy—injections of growth hormone into the body. Growth hormone—known as somatotropin—can be injected by t... Read More

Clinical virology

Image Virology is the study of viral – submicroscopic, parasitic particles of genetic material contained in a protein coat and virus-like agents. The ability to detect nucleic acids has had and still has a major impact on diagnostics in clinical virology. Both quantitative and qualitative techniques, w... Read More

Histopathology techniques

Image Histopathology is the diagnosis and study of diseases of the tissues, and involves examining tissues and/or cells under a microscope. Histopathologists are responsible for making tissue diagnoses and helping clinicians manage a patient's care. It is the examination of biological tissues in order to observe the appearance of diseased cells in microscopic detail. ... Read More

Laryngotracheal stenosis

Image Laryngotracheal stenosis refers to abnormal narrowing of the central air passageways. It can develop when scar tissue forms in a person’s trachea due to prolonged intubation — when a breathing tube is inserted into the trachea to help maintain breathing during a medical procedure — or from a tracheostomy, which is a surgery to create an opening in the neck to access the trachea. Our physicians will typically address any underlying medical conditions before treating the stenosis. The most common symptom of laryngotracheal stenosis is gradually-worsening breathlessness (dysp... Read More

Renal Transplantation on Long-term dialysis

Image A survey in Japan reported that the patients undergoing dialysis (HD) are increasing every year, and the number has reached 329,609 at the end of 2016. Out of them, 26,313 patients were undergoing longterm HD (LHD; 20 or more years), which is 8.3% of the total number. The number of deceased donor RTx (DRTx) did not increase, while the number of patients enrolled in the waiting list for DRTx reached approximately 13,000. Considering the Mean Waiting Period, LHD patients morbidity and mortality a study was designed by Koichi Kozaki, et al. to investigate the results of RTx in LHD patients. Ni... Read More

Immunosupressive drugs

Image Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications are drugs that inhibit or prevent activity of the immune system.They are also administered as posttransplantory immunosuppressants to prevent the acute transplant rejection and graft-versus-host disease. Immunosuppressive drugs are given in two phases; an initial induction phase involving a high dose, and a later maintenance phase which involves using the drug in the long term at a lower dose. All current immunosuppressive drugs come with limitations. One of the major limitation... Read More

STUDY OF VIRUSES

Image The study of virus is known as virology.It gives brief description about viral – submicroscopic, parasitic particles of genetic material contained in a protein coat and virus like agents. It focuses on the following aspects of viruses: their structure, classification and evolution, their ways to infect and exploit host cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. Virology is considered to be a subfield of microbiology or of medicine. ... Read More

THE STUDY OF FUNGI

Image The study of fungi is known as Mycology. It is the branch of biology concerned with the study of fungi, including their genetic and biochemical properties, their taxonomy and their use to humans as a source for tinder, traditional medicine, food, and entheogens, as well as their dangers, such as toxicity or infection. For centuries, certain mushrooms have been documented as a folk medicine in China, Japan, and Russia. Although the use of mushrooms in folk medicine is centered largely on the Asian continent, people in other parts of the world like the Middle East, Poland, and Belar... Read More

STUDY OF MICROORGANISMS IN MEDICAL ASPECT

Image Medical microbiology is a branch of medical science concerned with the prevention, diagnosis and treatment of infectious diseases. The microbes and the branch of microbiology are the most studied due to their great importance to medicine. Medical microbiology studies growth and development of the infectious disease in a patient and in human population  known as epidemiology. It is associated to the study of disease pathology and immunology. Similar sections cover virology, mycology, and parasitology. In each section, the introductory chapters stress the mechanisms of infectio... Read More

THE STUDY OF BACTERIA

Image The study of bacteria is known as Bacteriology, it is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species. Because of the similarity of thinking and working with microorganisms other than bacteria, such as protozoa, fungi, and viruses, there has been a tendency for the field of bacteriology to extend as microbiology. Bacteriology evolved from physicians need... Read More

Conservative Treatment of Hydatid Cyst in Pregnancy: Case Report

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Contemporary Review of Buried Penis Repair

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Fertility Preservation in Female Cancer Patients: A Retrospective Study from Iran

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Penile Enlargement Surgery: Is It Feasible?

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Healthy red blood cells owe their shape to muscle-like structures

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

Effects of feeding yeasts on blood physiology and gut microbiota of rainbow trout

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

Regulation of Blood Volume by Renal Excretion of Water and Sodium

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

Physiology of blood

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

The Endocrine System of the Human Body

Image Endocrinology & Diabetes Research is a peer-reviewed, open-access journal focused on publishing articles in all aspects of Type 1 and Type 2 Diabetes, Diabetic Nephropathy and retinopathy, Gestational Diabetes and Endocrinology. Introduction to the Endocrine System: The endocrine system, along with the nervous system, functions in the regulation of body activities. The nervous system acts through electrical imp... Read More

Role of Glucose in Daily life

Image Endocrinology & Diabetes Research is a peer-reviewed, open-access journal focused on publishing articles in all aspects of Type 1 and Type 2 Diabetes, Diabetic Nephropathy and retinopathy, Gestational Diabetes and Endocrinology. Glucose comes from the Greek word for "sweet." It's a type of sugar you get from foods you eat, and your body uses it for energy. As it travels through your bloodstream to your cells, it's called blo... Read More

Role of DM in Daily life

Image Endocrinology & Diabetes Research is a peer-reviewed, open-access journal focused on publishing articles in all aspects of Type 1 and Type 2 Diabetes, Diabetic Nephropathy and retinopathy, Gestational Diabetes and Endocrinology. DM is defined as a Diabetes mellitus is a disorder in which blood sugar (glucose) levels are abnormally high because the body does not produce enough insulin to meet its needs. Dietary habits and sede... Read More

Role of Insulin in Daily life

Image Endocrinology & Diabetes Research is a peer-reviewed, open-access journal focused on publishing articles in all aspects of Type 1 and Type 2 Diabetes, Diabetic Nephropathy and retinopathy, Gestational Diabetes and Endocrinology. Insulin is a naturally-occurring hormone secreted by the pancreas. Insulin is required by the cells of the body in order for them to remove and use glucose from the blood. Cells use glucose to produce ener... Read More

Sexual harassment : A self Loss

Image Sexual harassment is a type of harassment technique that relates to a sexual nature and the unwelcome or inappropriate promise of rewards in exchange for sexual favors. Sexual harassment includes a range of actions from mild transgressions to sexual abuse or assault. Harassment can occur in many different social settings such as the workplace, the home, school, churches, etc. Harassers or victims may be of any gender. This type of harassment leads to severe scars. Sexual and Emotional Trauma is caused due to sexual abuse an... Read More

Role of Fecal Calprotectin as a Bio-marker of Intestinal Inflammation in Inflammatory Bowel Disease

Image The Journal focuses on inflammatory bowel disease, calprotectin, biological markers, gastrointestinal diseases, and feces/chemistry. . Calprotectin is a protein released by a type of white blood cell called a neutrophil. Inflammatory bowel disease (IBD) is an umbrella term used to describe disorders that involve chronic inflammation of your digestive tract. A bio-marker or biological marker is a measurable indicator of some biological state or condition. Biomarkers ar... Read More

Intestinal Barrier Dysfunction in Inflammatory Bowel Diseases

Image The Journal focuses on ascariasis, trichuriasis, hookworm disease, and anemia. Ascariasis is an infection of the small intestine caused by Ascaris lumbricoides, which is a species of roundworm. Roundworms are a type of parasitic worm. Infections caused by roundworms are fairly common. Ascariasis is the most common roundworm infection. Trichuriasis, also known as whipworm infection, it is an infection by the parasitic worm Trichuris trichiura (whipworm). If infection i... Read More

Prayer, Meditation, and Anxiety: Durkheim Revisited

Image The Journal focuses on religion, prayer, meditation, anxiety, mental health. Religion is a social-cultural system of designated behaviors and practices, morals, worldviews, texts, sanctified places, prophecies, ethics, or organizations that relates humanity to supernatural, transcendental, or spiritual elements. Prayer is an invocation or act that seeks to activate a rapport with an object of worship through deliberate communication. In the narrow sense, the term refers t... Read More

Antibiotics

Image Antibiotics Anti-inflammatory (or antiinflammatory) is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Nonsteroidal anti-inflammatory drugs Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase&... Read More

Anti-inflammatory drugs

Image Anti-inflammatory drugs Anti-inflammatory (or antiinflammatory) is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Nonsteroidal anti-inflammatory drugs Nonsteroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyc... Read More

Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation

Image The Journal focuses on mindfulness, meditation, psychotherapy, neuroimaging, contemplative science, adverse effects, media hype, and misinformation. Mindfulness is the psychological process of purposely bringing one's attention to experiences occurring in the present moment without judgment which one can develop through the practice of meditation and through other training. Meditation is a practice where an individual uses a technique – such as mindfulness, or f... Read More

Hysteroscopic Resection of a Giant Cervical Polyp with Preservation of Hymen

Image Journal of Genital System & Disorders open access journal, peer-reviewed journal that aims to publish research dealing with Genital research which covers a wide variety of specialties such as: Obstetrics, Gynecology, Reproductive Biology, Adolescent and Pediatric Gynecology, Biochemistry of Reproductive Science, Cervical Pathology, Cervical Pathology & Colposcopy, Congenital Anomalies, Genital Disorders, Genital Oncology, Infertility etc. Cervical polyps... Read More

Uterine Rupture in a Second Trimester Twin Pregnancy after Laparoscopic Myomectomy

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Metabolic Syndrome in Adolescents with Type 1 Diabetes Mellitus in a Mixed Population: Are Girls at a Higher Risk?

Image Journal of Endocrinology & Diabetes Research (ISSN: 2470-7570): is Bi-annual journal is going to release its special issue in the month of January during coming of New Year 2020. Since its inception in the year 2015, the journal has been publishing several scholarly articles and International conference proceedings. The editorial team of the journal is planning to compile a special issue based research activities... Read More

Embryo Implantation and Inhibin Dimers (Activin) as Diagnosis of Ectopic Pregnancy

Image Journal of Endocrinology & Diabetes Research (ISSN: 2470-7570): is Bi-annual journal is going to release its special issue in the month of January during coming of New Year 2020. Since its inception in the year 2015, the journal has been publishing several scholarly articles and International conference proceedings. Embryo implantation is necessary for the successful formation of pregnancy. Ectopic implantation e... Read More

Haemophilia B PMS1 Gene SNPs Predictions through Insilico Approach at Proteomics Levels

Image Blood Research & Hematologic Diseases has announced almost 50% discount on article processing charge to commemorate its Anniversary. On behalf of the Blood Research & Hematologic Diseases, the editor of journal is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the year-long celebrations. During this year we look forward to taking some initiati... Read More

Evaluation of Anticoagulant and Antiplatelet Activity of Pisum sativum Pod Extract

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

The Importance of Internships: Ensuring Informatics Students’ Future Success

Image The Importance of Internships: Ensuring Informatics Students’ Future Success Journal of Health Informatics & Management is a scholarly peer-reviewed, academic journal that publishes original research articles undergoing peer review process with the help of experts in the field of Health Informatics. With so many people looking towards furthering their education and with all of the demands the recent federal mandates for... Read More

Conference Announcement on Dermatology & Cosmetology

Image Conference Announcement on Dermatology & Cosmetology Journal of Health Informatics & Management is a scholarly peer-reviewed, academic journal that publishes original research articles undergoing peer review process with the help of experts in the field of Health Informatics. Cosmetology and Dermatology, Reconstructive and Plastic Surgery, Hair Care and Transplant experts, skin care and Laser technology, Business approach... Read More

ANTISEPTICS

Image Antiseptics Antiseptics are antimicrobial substances that are applied to living tissue/skin to reduce the possibility of infection, sepsis, or putrefaction. Antiseptics are generally distinguished from antibiotics by the latter's ability to safely destroy bacteria within the body, and from disinfectants, which destroy microorganisms found on non-living objects. Some antiseptics are true germicides, capable of destroying microbes (bacteriocidal), while others are bacteriostatic... Read More

Turmeric as an antibiotic

Image Turmeric as an antibiotic Turmeric is a flowering plant, Curcuma longa of the ginger family, Zingiberaceae, the roots of which are used in cooking. The plant is a perennial, rhizomatous, herbaceous plant native to the Indian subcontinent and Southeast Asia, that requires temperatures between 20 and 30 °C (68 and 86 °F) and a considerable amount of annual rainfall to thrive. Plants are gathered each year for their rhizomes, some for propagation in the followi... Read More

FACIAL PALSY

Image The term facial palsy generally refers to weakness of the facial muscles, mainly resulting from temporary or permanent damage to the facial nerve. When a facial nerve is either non-functioning or missing, the muscles in the face do not receive the necessary signals in order to function properly. This results in paralysis of the affected part of the face, which can affect movement of the eye and/or the mouth, as well as other areas. There are differ... Read More

BONE MARROW

Image Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production or hematopoiesis. The composition of marrow is dynamic, as the mixture of cellular and non-cellular components. It is composed of hematopoietic cells, ma... Read More

Fighting the War on Drugs:What Weapons for Analysis and Detection?

Image The abuse of drugs has become one of the most serious socialproblems in the world. According to the “United Nations Office on Drugs and Crime” (UNODC) latest report, between 149 and 272 million people used illicit substances at least once in the year 2008.The world population of “Problem drug users”, defined as regular users of illicit substances is estimated at between 15 and 39 million. Amphetamines, cocaine, opiates and cannabis are the most abused substances. In addition non-medical use of prescription drugs is reportedly a growing health problem in a number of d... Read More

Solid Phase Extraction and Analysis of THC and Metabolites from Whole Blood using a Novel Automated Procedure using Liquid Chromatography and Tandem Mass Spectrometry(LC-MS/MS)

Image In this study, solid phase extraction (SPE) is described using a novel automated procedure to isolate tetrahydrocannabininol and its metabolites from whole blood samples. SPE was performed on an automated system after samples of whole blood were precipitated with acetonitrile. The system was programmed to condition the SPE columns with methylene chloride, methanol,de-ionized (DI) water, and aqueous phosphate buffer (0.1 M pH 7). The samples were loaded by the robot after which the SPE columns were washed with DI water, aqueous phosphate buffer and dried also by the same unit. The journal ha... Read More

Hyperglycemia and Tumor Energy Metabolism

Image Precise and critical analysis of biomedical data is crucial in our understanding of the pathological metabolism and necessary elements in the progress of a new drug development. Therefore this new open access journal (Journal of Pharmacological & Biomedical Analysis) is an important and welcome initiative for a new communication platform of research community allowing the rapid exchange of the scientific data. Precise and critical analysis of biomedical data is crucial in our understanding of the pathological metabolism and necessary elements in the progress of a new drug development. T... Read More

Availability of Different Strengths of Anti Malarial Preparations in Pakistan: Implication for Patient Safety

Image Pakistan is among the moderately malaria endemic countries and malaria is the second most commonly reported diseases from public sector healthcare facilities. Few of the key factors in controlling malaria and reducing related morbidity and mortality rate includes early diagnosis, appropriate treatment and good quality patient care services. But, polypharmacy, peer influence, patient demands, lack of appropriate diagnosis and treatment based on clinical impression and self-medication are few of the most important factors leading towards irrational drug use in Pakistan. Malaria is usually dia... Read More

CSF ANALYSIS

Image Cerebrospinal fluid (CSF) analysis is a way of looking for conditions that affect your brain and spine. CSF is produced by the choroid plexus in the brain and then reabsorbed into your bloodstream. The fluid is completely replaced every few hours. In addition to delivering nutrients, CSF flows around your brain and spinal column, providing protection and carrying away waste. A CSF sample is commonly collected by performing a lumbar puncture, which is also known as... Read More

CREATININE CLEARANCE TEST

Image  Creatinine is a waste product produced by muscles. Creatinine is removed from the body by the kidneys, release it into the urine. The creatinine clearance is a test that allows doctor to assess your kidney function. The clearance of substance may be defined as the volume of blood or plasma cleared of the substance found in one minute excretion of urine. It is usually measured using both a blood tes... Read More

Yoga as an Alternative and Complementary Therapy for Patients Suffering From Anxiety: A Systematic Review

Image The Journal focuses on yoga, anxiety, pranayama, stress, and breathing. Yoga is a group of physical, mental, and spiritual practices or disciplines. Anxiety is your body's natural response to stress. It's a feeling of fear or apprehension about what's to come. The first day of school, going to a job interview, or giving a speech may cause most people to feel fearful and nervous. Pranayama is the practi... Read More

Canadian Digestive Health Foundation Public Impact Series: Gastroesophageal reflux disease in Canada: Incidence, prevalence, and direct and indirect Economic impact

Image Gastroenterology is the official medical journal of the American Gastroenterological Association. Its first issue was published in 1943. It is currently published by Elsevier. According to the Journal Citation Reports, the journal has a 2017 impact factor of 20.877, ranking it first among 76 journals in the category "... Read More

Essential medicine

Image Essential  medicine Essential medicines, as defined by the World Health Organization (WHO), are the medicines that "satisfy the priority health care needs of the population". These are the medications to which people should have access at all times in sufficient amounts. The prices should be at generally affordable levels.Since 1977, the WHO has published a model list of essential medicines, with the current (2019) list for adult patients containing over 400 medicines.Since 2007, a separate list of medicines i... Read More

Homeopathy medicine

Image Homeopathy medicine Homeopathy  is a pseudoscientificsystem of alternative medicine. It was created in 1796 by Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a disease in healthy people would cure similar symptoms in sick people; this doctrine is called similia similibus curentur, or "like cures like".Homeopathic preparations are termed remedies and are made using a process called homeopathic dilution. This process involves repeatedly diluting a chosen ... Read More

Akward Postures And Risk Of Musculoskeletal Disorders

Image Working posture is the posture adopted by an employee while performing work tasks. It can be altered often, or a single posture can be sustained for an extended time. The human body can be represented by segments, such as an arm, forearm, thigh or trunk, connected to other segments by joints. Working posture can be described by angles between body segments. Musculoskeletal load related to occupational work is very often a cause in the development of work-related ... Read More

Notification-Rapid Publication

Image The Scitechnol Journal named Archives of Transplantation is accepting submissions related to the broader scope of the subject Experimental and Clinical Transplantation for the Volume 4 Issue 1. Hurry up and Submit Manuscript at transplantation@scholarres.org by 15 February, 2020. You are free to share any type of article (Research articles, Review articles, Case r... Read More

Article Compilation Notification

Image The Scitechnol- Journal of Otology and Rhinology accepting submissions related to the broader scope of the subject ENT (Ear, Nose and Throat) for the Volume 9 Issue 1. Hurry up and Submit Manuscript at otorhino@peerjournal.org by 15 February, 2020. You are free to share any type of article (Research articles, Review articles, Case reports, Short Communication and Opinion article) you wish with us as per ... Read More

FREE RADICAL THEORY OF AGING

Image The free radical theory of aging (FRTA) states that organisms age because cells accumulate free radical damage over time. Denham Harman first proposed the free radical theory of aging in the 1950s. Free radicals that are thought to be involved in the process of aging include superoxide and nitric oxide. An increase in superoxide affects ... Read More

Cataract is mostly due to aging

Image A cataract is a clouding of the lens in the eye which leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Symptoms may include faded colors, blurry or double vision, halos around light, trouble with bright lights, and trouble seeing at night. Cataracts are most commonly due to aging, but may also occur due to t... Read More

Ayurveda

Image Ayurveda Ayurveda is a system of medicine with historical roots in the Indian subcontinent. Globalized and modernized practices derived from Ayurveda traditions are a type of alternative medicine. In countries beyond India, Ayurvedic therapies and practices have been integrated in general wellness applications and in some cases in medical use. The main classical Ayurveda texts begin with accounts of the transmission of medical knowledge from the Gods to sages, and then to human physicians. In Sushruta Samhita (Sush... Read More

Psychology Stress

Image Psychology Stress In psychology, stress is a feeling of strain and pressure. Stress is a type of psychological pain. Small amounts of stress may be desired, beneficial, and even healthy. Positive stress helps improve athletic performance. It also plays a factor in motivation, adaptation, and reaction to the environment. Excessive amounts of stress, however, may lead to bodily harm. Stress can increase the risk of strokes, heart attacks, ulcers, and mental illnesses such as depression. Stres... Read More

Journal of Genital System & Disorders Open Access

Image Journal of Genital System & Disorders open access journal, peer-reviewed journal that aims to publish research dealing with Genital research which covers a wide variety of specialties such as: Obstetrics, Gynecology, Reproductive Biology, Adolescent and Pediatric Gynecology, Biochemistry of Reproductive Science, Cervical Pathology, Cervical Pathology & Colposcopy, Congenital Anomalies, Genital Disorders, Genital Oncology, Infertility etc. Current Researc... Read More

Genital System & Disorders

Image Journal of Genital System & Disorders is a peer-reviewed scholarly journal and aims to publish the most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all major themes pertaining to Genital System & Disorders and making them available online freely without any restrictions or any other subscriptions to researchers worldwide. ... Read More

Special Issue on Blood Research & Hematologic Diseases

Image Blood Research & Hematologic Diseases has announced almost 50% discount on article processing charge to commemorate its Anniversary. On behalf of the Blood Research & Hematologic Diseases, the editor of journal is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the year-long celebrations. During this year we look forward to taking some initiati... Read More

Blood Research & Hematologic Diseases

Image Journal of Blood Research & Hematologic Diseases is an open access journal and celebrating the 5th Anniversary, an esteemed journal which mainly deals with Blood Research & Hematologic Diseases. This Journal of Blood Research & Hematologic Diseases is a peer reviewing processing journal and publishes the articles on Blood Vessels, Circulatory System, Haematology, Haematopoiesis, Haemoglobin, Haemostasis ... Read More

Endocrinology & Diabetes Research

Image Journal of Endocrinology & Diabetes Research (ISSN: 2470-7570): is Bi-annual journal is going to release its special issue in the month of January during coming of New Year 2020. Since its inception in the year 2015, the journal has been publishing several scholarly articles and International conference proceedings. Dental hygiene is an essential part of good health. For diabetics, problems with the teeth and gum... Read More

DEMENTIA

Image Dementia is a syndrome in which there is deterioration in memory, thinking, behaviour and the ability to perform everyday activities. Consciousness is not affected. Dementia results from a variety of diseases and injuries that primarily or secondarily affect the brain, such as Alzheimer's disease or stroke. Dementia affects each person in a different way, depending upon the impact of the disease and the person’s personality before becoming ... Read More

LIVER FUNCTION TESTS

Image  Liver function tests (LFTs) are groups of blood tests that provide information about the state of a patient's liver. These tests can be used to detect the presence of liver disease, distinguish among different types of liver disorders, gauge the extent of known liver damage, and monitor the response to treatment. These tests include albumin, bilirubin, the liver transaminases aspartate transaminase (AST or SGOT) a... Read More

EXERCISE

Image Exercise is any bodily activity that enhances or maintains physical fitness and overall health and wellness. It is performed for various reasons, to aid growth and improve strength, preventing aging, developing muscles and the cardiovascular system, honing athletic skills, weight loss or maintenance, improving health and also for enjoyment. In terms of health benefits, the amount of recommended exercise depends upon the goal, the type of exercise, and the age of th... Read More

DNA PROFILING

Image DNA profiling and matching of physical data, such as fingerprints, are used in solving all crime types ranging from housebreaking and car crime to assaults, murder and rape. The forensic scientists will look for suitable samples at a crime scene, examining such items as weapons, clothing, hair or anything else from which they can obtain body cells... Read More